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High-Dose Chemotherapy for Breast Cancer in Europe

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Molecular Biology of Hematopoiesis 6

Abstract

In the last few years high-dose chemotherapy expanded throughout Europe as a treatment option for breast carcinoma patients. In 1993, 400 patients were reported during the annual European survey, while in 1996 more than 2100 patients received this treatment modality, and we may foresee that at least 2500 women underwent this procedure in 1998. From the European Group for Blood and Marrow Transplantation (EBMT) Registry data base more than 95% of the high-dose programs have been conducted with the support of Peripheral Blood Progenitor Cells (PBPC) last year, with a minority of patients receiving Autologous Bone Marrow Transplantation (ABMT) as hematopoietic support. This data are slightly different from those recently reported by the Autologous Bone Marrow Transplantation Registry of North America,1 indicating that 25% of the patients received ABMT, alone or in combination with PBPC (data referring to 1995). Patients selected for high-dose chemotherapy programs are equally divided into metastatic and adjuvant ones, with 10% with inflammatory breast carcinoma.

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© 1999 Springer Science+Business Media New York

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Rosti, G. et al. (1999). High-Dose Chemotherapy for Breast Cancer in Europe. In: Abraham, N.G., Tabilio, A., Martelli, M., Asano, S., Donfrancesco, A. (eds) Molecular Biology of Hematopoiesis 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4797-6_19

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  • DOI: https://doi.org/10.1007/978-1-4615-4797-6_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7173-1

  • Online ISBN: 978-1-4615-4797-6

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