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Enzymology and Molecular Biology of Carbonyl Metabolism 7 pp 343–350Cite as

Amphibian Alcohol Dehydrogenase

Purification and Characterization of Classes I and III from Rana perezi

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 463))

Abstract

Alcohol dehydrogenase (ADH) catalyses the reversible interconversion of a variety of alcohols and their corresponding aldehydes and ketones, and is widely distributed in organisms. It has been detected in all animals, in plants, and eukaryotic and prokaryotic microorganisms. In vertebrates the ADH system is complex, with at least seven different enzymatic classes (Jörnvall and Höög, 1995, Kedishvili et al., 1997). The study in sub- mammal species is of interest to understand the relationship between the classes found in mammals and the evolutionary origins of the present structures. Moreover, since the enzyme exhibits a wide substrate specificity, the comparative study of the enzymes from distant species may provide valuable information on the function of the enzyme, and how it may change among groups of vertebrates to adapt to different physiological needs.

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology Faculty of Sciences, Universität Autönoma de Barcelona, 08193, Bellaterra, Spain

    Josep Maria Peralba, Bernat Crosas, Susana E. Martinez, Pere Julià, Jaume Farrés & Xavier Parés

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  1. Josep Maria Peralba
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  2. Bernat Crosas
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  3. Susana E. Martinez
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  4. Pere Julià
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  5. Jaume Farrés
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  6. Xavier Parés
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Editor information

Editors and Affiliations

  1. Purdue University, West Lafayette, Indiana, USA

    Henry Weiner

  2. Philipps University of Marburg, Marburg, Germany

    Edmund Maser

  3. Indiana University School of Medicine, Indianapolis, Indiana, USA

    David W. Crabb

  4. University of South Dakota School of Medicine, Vermillion, South Dakota, USA

    Ronald Lindahl

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© 1999 Springer Science+Business Media New York

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Peralba, J.M., Crosas, B., Martinez, S.E., Julià, P., Farrés, J., Parés, X. (1999). Amphibian Alcohol Dehydrogenase. In: Weiner, H., Maser, E., Crabb, D.W., Lindahl, R. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 7. Advances in Experimental Medicine and Biology, vol 463. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4735-8_42

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  • DOI: https://doi.org/10.1007/978-1-4615-4735-8_42

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7146-5

  • Online ISBN: 978-1-4615-4735-8

  • eBook Packages: Springer Book Archive

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