Improvements in Human Health Through Production of Human Milk Proteins in Transgenic Food Plants

  • Takeshi Arakawa
  • Daniel K. X. Chong
  • Charles W. Slattery
  • William H. R. Langridge
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 464)


Plants are particularly suitable bioreactors for the production of proteins, as their eu-karyotic nature frequently directs the appropriate post-translational modifications of recombinant proteins to retain native biological activity. The autotrophic growth of plants makes this in vivo biosynthesis system economically competitive for supplementation or replacement of conventional production systems in the future. For the production of biologically active proteins, food plants provide the advantage of direct delivery via consumption of transformed plant tissues. Here we describe the production of recombinant human milk proteins in food plants for improvements in human nutrition and health, with emphasis on enhanced nutrition for non-breast fed infants as well as children and adults. Nutritional improvements in edible plants generated through advancements in recombinant DNA technology are rapidly repositioning the world for enjoyment of a more healthful diet for humans in all age groups.


Human Milk Whey Protein Milk Protein Infant Formula Total Soluble Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Takeshi Arakawa
    • 3
    • 4
  • Daniel K. X. Chong
    • 3
  • Charles W. Slattery
    • 1
    • 5
  • William H. R. Langridge
    • 3
    • 1
    • 4
    • 2
  1. 1.Department of BiochemistryLoma Linda UniversityLoma LindaUSA
  2. 2.Center for Molecular Biology and Gene Therapy, School of MedicineLoma Linda UniversityLoma LindaUSA
  3. 3.Center for Molecular Biology and Gene TherapyLoma Linda UniversityLoma LindaUSA
  4. 4.Department of Microbiology and Molecular GeneticsLoma Linda UniversityLoma LindaUSA
  5. 5.Department of PediatricsLoma Linda UniversityLoma LindaUSA

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