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Oscillations in Cerebral Haemodynamics

Implications for Functional Activation Studies

  • Chapter
Oxygen Transport to Tissue XXI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 471))

Abstract

The blood oxygenation level dependent (BOLD) contrast signal in functional magnetic resonance imaging (fMRI) provides highly spatially resolved deoxygenation maps of the activated cortex (Turner 1995). In common with many other activation measurement techniques, (including optical measurements) fMRI relies upon multiple repetition of the stimulus followed by signal averaging, baseline subtraction and extensive thresholding techniques to provide difference images of activation.

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References

  • Bandetti PA, Wong EC, Binder JR, Rao SM, Jesmanowicz A, Aaron EA, Lowry TF, Forster HV, Hinks RS, and Hyde JS (1995) Diffusion and Perfusion: Magnetic Resonance Imaging, Raven Press, New York, 335–349.

    Google Scholar 

  • Berne RM and Levy MN (1997) Cardiovascular Physiology (7th Edition), Mosby Year Book, St. Louis, p. 152.

    Google Scholar 

  • Buxton RB, Wong EC, and Frank LR (1998) Dynamics of blood flow and oxygenation changes during brain activation: The balloon model. Magn. Res. Med. 39:855–864.

    Article  CAS  Google Scholar 

  • Colier WNJM, Quaresima V, Barattelli G, Cavallari P, van der Sluijs M, and Ferrari M (1997) Detailed evidence of cerebral oxygenation changes in response to motor cortical activation revealed by a continuous wave spectrophotometer with 10 Hz temporal resolution. Proc. SPIE 2979:390–396.

    Article  CAS  Google Scholar 

  • Dóra E and Kovách AGB (1980) Metabolic and vascular volume oscillations in the cat cerebral cortex. Acta Physiol Acad Sci Hung 57:261–275.

    Google Scholar 

  • Essenpreis M, Elwell CE, Cope M, van der Zee P, Arridge SR, and Delpy DT (1993) Spectral dependence of temporal point spread functions in human tissues. Appl. Opt. 32(4):418–425.

    Article  PubMed  CAS  Google Scholar 

  • Firbank M, Okada E, and Delpy DT (1998) A theoretical study of the signal contribution of regions of the adult head to near infrared spectroscopy studies of visual evoked responses. Neuroimage 8: 69–78.

    Article  PubMed  CAS  Google Scholar 

  • Funk W and Intaglietta M (1983) Spontaneous arteriolar vasomotion In: Vasomotion and quantitative capil-laroscopy. (Messmer K, Hammersen F, Eds) Karger, Basel, pp. 66–82.

    Google Scholar 

  • Halsey JHJ and McFarland S (1974) Oxygen cycles and metabolic autoregulation. Stroke 5:219–225.

    Article  PubMed  Google Scholar 

  • Hoshi Y and Tamura M (1997) Fluctuations in the cerebral oxygenation state during the resting period in functional mapping studies of the human brain. Med. Biol. Eng. & Comp. 35:328–330.

    Article  CAS  Google Scholar 

  • Hudetz AG, Roman RJ, and Harder DR (1992) Spontaneous flow oscillations in the cerebral cortex during acute changes in mean arterial pressure. J. Cereb. Blood Flow & Metab. 12:491–499.

    Article  CAS  Google Scholar 

  • Hutton C, Howesman A, Joesphs O, Friston K, and Turner R (1998) The effect of inter-stimulus on signal response in fMRI. Proc ISMRM:S1430.

    Google Scholar 

  • Mayhew JE, Askew S, Zheng Y, Porrill J, Westby GW, Redgrave P, Rector D, and Harper RM (1996) Cerebral vasomotion: A 0.1 Hz oscillation in reflected light imaging of neural activity. Neuroimage 4:183–193.

    Article  PubMed  CAS  Google Scholar 

  • Meek JH, Elwell CE, Khan AJ, Romaya J, Wyatt JS, Delpy DT, and Zeki S (1994) Changes in occipital haemo-dynamics due to a visual stimulus detected by near infrared spectroscopy. J. Physiol. 479.P:.

    Google Scholar 

  • Okada E, Firbank M, Schweiger M, Arridge SR, Cope M, and Delpy DT (1997) Theoretical and experimental investigation of near infrared light propogation in a model of the adult head. Appl. Opt. 36:21–31.

    Article  PubMed  CAS  Google Scholar 

  • Schniff (1854) Ein accessorisches Arterienherz beim Kaninchen. Arch. Physiol. Heilk (Leipzig) XIII.523–527.

    Google Scholar 

  • Turner R (1995) Functional mapping of the human brain with magnetic resonance imaging. Seminars in The Neurosciences 7:179–194.

    Article  Google Scholar 

  • Vern BA, Schette WH, Leheta B, Juel VC, and Radulovacki M (1998) Low frequency oscillations of cortical oxidative metabolism in waking and sleep. J. Cereb. Blood Flow & Metab. 8, 2:215–226.

    Google Scholar 

  • Villringer A, Planck J, Hock C, Schleinkofer L, and Dirnagl U (1993) Near infrared spectroscopy (MRS)-a new tool to study hemodynamic changes during activation of brain function in human adults. Neuroscience Letters 154:101–104.

    Article  PubMed  CAS  Google Scholar 

  • Wray S, Cope M, Delpy DT, Wyatt JS, and Reynolds EOR (1988) Characterisation of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non invasive monitoring of cerebral oxygenation. Biochim. Biophys. Acta 933:184–192.

    Article  PubMed  CAS  Google Scholar 

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© 1999 Springer Science+Business Media New York

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Elwell, C.E., Springett, R., Hillman, E., Delpy, D.T. (1999). Oscillations in Cerebral Haemodynamics. In: Eke, A., Delpy, D.T. (eds) Oxygen Transport to Tissue XXI. Advances in Experimental Medicine and Biology, vol 471. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4717-4_8

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  • DOI: https://doi.org/10.1007/978-1-4615-4717-4_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7137-3

  • Online ISBN: 978-1-4615-4717-4

  • eBook Packages: Springer Book Archive

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