Abstract
In the last few years near infrared spectroscopy (NIRS) has become a more widespread tool to map the human brain function, in particular the motor cortex areas (Gratton et al., 1995; Hirth et al., 1996; Obrig et al., 1996; Colier et al., 1997) and visual cortex areas (Kato et al., 1993; Hoshi et al., 1993; Meek et al., 1995; Wenzel et al., 1996; Gratton et al., 1998). In these studies it was shown that NIRS is able to detect changes in cerebral oxygenation due to visual stimulation in the occipital cortex. Most subjects respond to a visual stimulus with an increase in the oxyhemoglobin concentration ([O2Hb]) and a decrease in the deoxy-hemoglobin concentration ([HHb]) of smaller magnitude than the [O2Hb] change (Wenzel et al., 1996).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Biswal B, Hudetz AG, Zerrin Yetkin F, Haughton VM, and Hyde JS (1997) Hypercapnia reversibly suppresses low-frequency fluctuations in the human motor cortex during rest using echo-planar MRI. J Cereb Blood Flow Metab 17:301–308.
Colier WNJM, Quaresima V, Barattelli G, Cavallari P, Sluijs M van der, and Ferrari M (1997) Detailed evidence of cerebral hemoglobin oxygenation changes in response to motor cortical activation revealed by a continuous wave spectrophotometer with 10 Hz temporal resolution. SPIE 2979:390–396.
Delpy DT and Cope M (1997) Quantitation in tissue near-infrared spectroscopy. Phil Trans R Soc Lond B 261:649–659.
Delpy DT, Cope M, Zee P van der, Arridge S, Wray S, and Wyatt J (1988) Estimation of optical pathlength through tissue from direct time of flight measurements. Phys Med Biol 33:1433–1442.
Elwell CE, Springett R, Hillman E, and Delpy DT (1998) Oscillations in cerebral haemodynamics: implications for functional activation studies. In: Abstract book ISOTT 1998, Budapest, p. 47.
Gratton G, Fabiani M, Friedman D, Franceschini MA, Fantini S, Corballis P, and Gratton E (1995) Rapid changes of optical parameters in the human brain during a tapping task. J Cogn Neurosc 7:446–456.
Gratton G, Fabiani M, Goodman-Wood MR, and Desoto MC (1998) Memory-driven processing in human medial occipital cortex: An event-related optical signal (EROS) study. Psychophysiology 35:348–351.
Hirth C, Obrig H, Villringer K, Thiel A, Bernarding J, Mühlnickel W, Flor H, Dirnagl U, and Villringer A (1996) Non-invasive functional mapping of the human motor cortex using near-infrared spectroscopy. NeuroReport 7:1977–1981.
Hoshi Y and Tamura M (1993) Dynamic multichannel near-infrared optical imaging of brain activity. J Appl Physiol 75:1–5.
Kato T, Kamei A, Takashima S, and Ozaki T (1993) Human visual cortical function during photic stimulation monitoring by means of near-infrared spectroscopy. J Cereb Blood Flow Metab 13:516–520.
Meek JH, Elwell CE, Khan MJ, Romaya J, Wyatt JS, Delpy DT, and Zeki S (1995) Regional changes in cerebral haemodynamics as a result of a visual stimulus measured by near infrared spectroscopy. Proc R Soc Lond B261:351–356.
Obrig H, Hirth C, Junge-Hülsing JG, Döge C, Wolf T, Dirnagl U, and Villringer A (1996) Cerebral oxygenation changes in response to motor stimulation. J Appl Physiol 81:1174–1183.
Savitzky A and Golay M JE (1964) Smoothing and differentation of data by simplified least squares procedures. Anal Chem 36:1627–1639.
Sluijs MC van der, Colier WNJM, Houston RJF, and Oeseburg B (1998) A new and highly sensitive continuous wave near infrared spectrophotometer with multiple detectors. SPIE 3194:63–72.
Wenzel R, Obrig H, Ruben J, Villringer K, Thiel A, Bernarding J, Dirnagl U, and Villringer A (1996) Cerebral blood oxygenation changes induced by visual simulation changes. J Biomed Opt 1:399–404.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Springer Science+Business Media New York
About this chapter
Cite this chapter
Colier, W.N.J.M. et al. (1999). Cortical Blood Oxygenation Changes in the Left and Right Occipital Area Induced by Selective Visual Stimuli in Humans. In: Eke, A., Delpy, D.T. (eds) Oxygen Transport to Tissue XXI. Advances in Experimental Medicine and Biology, vol 471. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4717-4_5
Download citation
DOI: https://doi.org/10.1007/978-1-4615-4717-4_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-7137-3
Online ISBN: 978-1-4615-4717-4
eBook Packages: Springer Book Archive