Abstract
Early recordings with oxygen electrodes show that under steady state conditions, tissue oxygen tension (Po2) undergoes spontaneous fluctuations (Clark, 1958; Cooper et al., 1966; Hardwick, 1996; Misrahy et al, 1962). These oscillations differ between organs and species but a general pattern of lā10c/min with an amplitude of 10ā30% of the mean Po2 has been observed (Morita-Tsuzuki et al., 1992; Hasibeder et al., 1994; Braun et al., 1992; Eickhoff and Jacobsen, 1982; Towell et al., 1976; Manil et al., 1984). Recordings of oscillations in flowmotion by other methods such as laser Doppler and magnetic resonance imaging (MRI) (Beinder et al, 1994; Morita-Tsuzuki et al., 1992; Hudetz et al., 1992; Biswal and Hudetz, 1996; Ren et al., 1993; Biswal et al., 1995, 1996) appear to exhibit similar frequencies of oscillation as the Po2.
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Karkan, D.M., van Breemen, C., Skarsgard, P.L., Lagaud, G.J., Hardwick, D.F. (1999). A Link between Vasomotion and Spontaneous Oscillations of Oxygen in Rat Brain. In: Eke, A., Delpy, D.T. (eds) Oxygen Transport to Tissue XXI. Advances in Experimental Medicine and Biology, vol 471. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4717-4_13
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