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Hormonal Stimulation of the Mouse Mammary Gland

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Methods in Mammary Gland Biology and Breast Cancer Research

Abstract

The intent of this chapter is to illustrate the use of a pituitary isograft to provide hormonal stimulation of the mammary gland. This chapter describes the procedure for implanting the pituitary gland under the kidney capsule and the consequences of the grafted pituitary for normal development of the mammary gland and for facilitating neoplastic transformation induced by chemical carcinogens.

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Abbreviations

TEB:

terminal end buds

MMTV:

mouse mammary tumor virus

DMBA:

dimethylbenzanthracene

References

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Author information

Authors and Affiliations

  1. Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, Texas, 77030, USA

    Daniel Medina & Frances Kittrell

Authors
  1. Daniel Medina
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  2. Frances Kittrell
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, 14263, USA

    Margot M. Ip

  2. Roswell Park Cancer Research Institute, Buffalo, New York, USA

    Bonnie B. Asch

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© 2000 Springer Science+Business Media New York

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Medina, D., Kittrell, F. (2000). Hormonal Stimulation of the Mouse Mammary Gland. In: Ip, M.M., Asch, B.B. (eds) Methods in Mammary Gland Biology and Breast Cancer Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4295-7_10

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  • DOI: https://doi.org/10.1007/978-1-4615-4295-7_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6927-1

  • Online ISBN: 978-1-4615-4295-7

  • eBook Packages: Springer Book Archive

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