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Angiogenesis pp 327–350Cite as

Therapeutic Angiogenesis for Ischemic Heart Disease

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 476))

Abstract

The de-novo formation of vessels (angiogenesis) and the remodelling of preexisting collateral vessels (arteriogenesis) are processes that occur naturally in ischemic heart disease. Promoting these processes by administration of various substances or other physical stimuli (therapeutic angiogenesis) may provide a future strategy for the treatment of ischemic vascular diseases. Mechanisms of angiogenesis and arteriogenesis, as well as trials of therapeutic angiogenesis in animal models and humans are reviewed.

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Authors and Affiliations

  1. Department of Experimental Cardiology, Max-Planck-Institute for Physiological and Clinical Research, Bad Nauheim, Germany

    Armin Helisch

  2. Division of Cardiovascular Medicine,Departments of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA

    J. Anthony Ware

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  1. Armin Helisch
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  1. University of Patras Medical School, Patras, Greece

    Michael E. Maragoudakis

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Helisch, A., Anthony Ware, J. (2000). Therapeutic Angiogenesis for Ischemic Heart Disease. In: Maragoudakis, M.E. (eds) Angiogenesis. Advances in Experimental Medicine and Biology, vol 476. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4221-6_27

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  • DOI: https://doi.org/10.1007/978-1-4615-4221-6_27

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  • Online ISBN: 978-1-4615-4221-6

  • eBook Packages: Springer Book Archive

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