Abstract
Thymidine phosphorylase (TP), also known as platelet-derived endothelial cell growth factor (PD-ECGF), is specifically involved in the reversible dephosphorylation of thymidine to thymine and 2-deoxy-D-ribose-1 -phosphate. It is a potent angiogenic factor shown to induce endothelial cell migration and proliferation (Moghaddam et al 1995).
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Sivridis, E. (2000). Thymidine Phosphorylase Activity in Normal, Hyperplastic and Neoplastic Endometrium - Correlation With Intratumoral Angiogenesis. In: Maragoudakis, M.E. (eds) Angiogenesis. Advances in Experimental Medicine and Biology, vol 476. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4221-6_24
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DOI: https://doi.org/10.1007/978-1-4615-4221-6_24
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