Skip to main content

Part of the book series: Springer Series on Stress and Coping ((SSSO))

Abstract

Most, if not all, clinicians in the field of traumatic stress would agree that sleep disturbances are among the most prominent and distressing complaints associated with post-traumatic stress disorder or PTSD. This recognition is formalized in the Diagnostic and Statistic Manual of Mental Disorders IV by the inclusion of nightmares and difficulty initiating and maintaining sleep as symptom criteria. Overall, a pathogenic role for sleep disturbance in PTSD is supported by the prominence of sleep-related symptoms, the association of traumatic incidents with sleep disruption, and the overlap of the effects of sleep deprivation and PTSD symptoms. Although the importance of sleep disturbance in PTSD may seem self evident, there has been uncertainty regarding the objective nature of sleep abnormalities in PTSD. Historically, the deficiency of data allowed for speculative hypotheses. Although uncertainty regarding the role of sleep in PTSD remains, the topic has been the subject of a number of recent investigations by an international group of investigators. Therefore, it seemed timely with the convening of the meeting that inspired this volume, the Second World Conference of the International Society for Traumatic Stress Studies that met in June 1996 in Israel, to address investigations of sleep and PTSD. Researchers who are actively investigating the topic were invited to participate. They included Ehud Klien of Israel who presented a longitudinal study of recent accident victims that included actigraphic and Polysomnographie sleep assessments. Thomas Hurwitz of the United States presented sleep laboratory evaluations of Vietnam combat veterans. Wybrand Op den Weld and J. M. H. de Groen of the Netherlands presented sleep and circadian studies of aging World War II Resistance fighters. Peretz Lavie of Israel presented a study of awakening thresholds from rapid eye movement or REM sleep in PTSD subjects, and this author (Thomas Mellman of the United States) reviewed sleep studies of combat veterans and more acutely affected subjects who had PTSD related to a natural disaster. Richard Ross of the United States could not attend but was involved in conceiving and planning the symposium.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Armitage, R., Rush, J. A., Trivedi, M., Cain, J.,& Roffwarg, H. (1994). The effects of nefazodone on sleep architecture in depression. Neuropsychopharmacology, 10, 123–127.

    PubMed  Google Scholar 

  • Brown, T. M.,& Boudewyns, P. A. (1996). Periodic limb movements of sleep in combat veterans with posttraumatic stress disorder. Journal of Traumatic Stress, 9, 129–136.

    Article  PubMed  Google Scholar 

  • Cartwright, R. D., Kravitz, H., Eastman, C. I.,& Wood, E. (1991). REM latency and the recovery from depression. Getting over divorce. American Journal of Psychiatry, 148, 1530–1535.

    PubMed  Google Scholar 

  • Cartwright, R. D., Monroe, L.J.,& Palmer, C. (1967). Individual differences in response to REM deprivation. Archives of General Psychiatry, 16, 297–303.

    Article  PubMed  Google Scholar 

  • Dagan, Y, Lavie, P.,& Bleich, A. (1991). Elevated awakening thresholds in sleep stage 3-4 in war-related posttraumatic stress disorder. Biological Psychiatry, 30, 618–622.

    Article  PubMed  Google Scholar 

  • David, D.,& Mellman, T. A. (1997). Dreams following Hurricane Andrew. Dreaming, 7, 209–214.

    Article  Google Scholar 

  • Davidson, J. R. T., Kudler, H., Smith, R., Mahorney, S. L., Lipper, S., Hammett, E., Saunders, W. B.,& Cavenar, J. O. (1990). Treatment of posttraumatic stress disorder with amitriptyline and placebo. Archives of General Psychiatry, 47, 259–266.

    Article  PubMed  Google Scholar 

  • Dow, B. M., Kelsoe J. R.,& Gillin J. C. (1996). Sleep and dreams in Vietnam PTSD and depression. Biological Psychiatry, 39, 42–50.

    Article  PubMed  Google Scholar 

  • Foulkes, W. D. (1962). Dream reports from different stages of sleep. Journal of Abnormal Social Psychology, 65, 14–25.

    Article  Google Scholar 

  • Glaubman, H., Mikulincer, M., Porat, A., Wasserman, O.,& Birger, M. (1990). Sleep of chronic posttraumatic patients. Journal of Traumatic Stress, 3, 255–263.

    Article  Google Scholar 

  • Green, B. L. (1993). Disasters and posttraumatic stress disorder. J. R. T. Davidson& E. B. Foa, (Eds.), Posttraumatic stress disorder DSM-IV and beyond. Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Hefez, A., Metz, L.,& Lavie, P. (1987). Long-term effects of extreme situational stress on sleep and dreaming. American Journal of Psychiatry, 144, 344–347.

    PubMed  Google Scholar 

  • Inman, D. J., Silver, S. M.,& Doghramji, K (1990). Sleep disturbance in post-traumatic stress disorder: A comparison with non-PTSD insomnia. Journal of Traumatic Stress, 3, 429–437.

    Article  Google Scholar 

  • Kinzie, J. D.,& Leung, P. (1989). Clonidine in Cambodian patients with posttraumatic stress disorder. Journal of Nervous and Mental Disorders, 177, 546–550.

    Article  Google Scholar 

  • Krakow, B., Tandberg, D., Cutchen, L., McBride, L., Hollifield, M., Lauriello, J., Schrader, R., Yau, C. L.,& Chang, D. T. (1997). Sleep Research, 26, 245.

    Google Scholar 

  • Kramer, M.,&Kinney, L. (1988). Sleep patterns in trauma victims with disturbed dreaming. Psychiatric Journal University of Ottawa, 13, 12–16.

    Google Scholar 

  • Kupfer, D.J. (1976). REM latency—a psychobiological marker for primary depressive disease. Biological Psychiatry, 11, 159–174.

    PubMed  Google Scholar 

  • Kupfer, D.J., Ehlers, C. L., Frank, E., Grochocinski, V.J., McEarchran, A. B.,& Buhari, A. (1994). Persistent effects of antidepressants: EEG sleep studies in depressed patients during maintenance treatment. Biological Psychiatry, 35, 781–793.

    Article  PubMed  Google Scholar 

  • Lerer, B., Bleich, A., Kotier, M., Garb, R., Hertzberg, M.,& Levin, B. (1987). Posttraumatic stress disorder in Israeli combat veterans. Effect of phenelzine treatment. Archives of General Psychiatry, 44, 976–981.

    Article  PubMed  Google Scholar 

  • Mellman, T. A., Kulick-Bell, R., Ashlock, L. E.,& Nolan, B. (1995a). Sleep events in combat-related posttraumatic stress disorder. American Journal of Psychiatry, 152, 110–115.

    PubMed  Google Scholar 

  • Mellman, T. A., David, D., Kulick-Bell, R., Hebding, J.,&Nolan, B. (1995b). Sleep disturbance and its relationship to psychiatric morbidity following Hurricane Andrew. American Journal of Psychiatry, 152, 1659–1663.

    PubMed  Google Scholar 

  • Mellman, T. A., Nolan, B., Hebding, J., Kulick-Bell, R.,& Dominguez, R. (1997). A polysomnographic comparison of veterans with combat-related PTSD, depressed men, and non-ill controls. Sleep, 20, 46–51.

    PubMed  Google Scholar 

  • Morrison, A. R., Sanford, L. D., Ball, W. A., Mann, G. L.,& Ross, R.J. (1995). Stimulus-elicited behavior in rapid eye movement sleep without atonia. Behavioral Neuroscience, 109, 972–979.

    Article  PubMed  Google Scholar 

  • Reynolds, C. F., Buysse, D.J., Kupfer, D.J., Hoch, C. C, Houch, P. R., Matzzie. J.,& George, C.J. (1990). Rapid eye movement sleep deprivation as probe in elderly subjects. Archives of General Psychiatry, 47, 1128–1136.

    Article  PubMed  Google Scholar 

  • Reynolds, C. F., Hoch, C. C, Buysse, D. J., Houch, P. R., Schlernitzauer, M., Pasternack, R. E., Frank, E., Mazumdar, S.,& Kupfer, D. J. (1993). Sleep after spousal bereavement: A study of recovery from stress. Biological Psychiatry, 34, 791–797.

    Article  PubMed  Google Scholar 

  • Rosen, J., Reynolds, C. F., Yeaer, A. L., Houck, P. R.,& Hurwitz, L. F. (1990). Sleep disturbances in survivors of the Nazi holocaust. American fournal of Psychiatry, 148, 62–66.

    Google Scholar 

  • Ross, R. J., Ball, W. A., Dinges, D. F., Kribbs, N. B., Morrison, A. R., Silver, S. M.,& Mulvaney, F. D. (1994a). Rapid eye movement sleep disturbance in posttraumatic stress disorder. Biological Psychiatry, 35, 195–202.

    Article  PubMed  Google Scholar 

  • Ross, R. J., Ball, W. A., Dinges, D. F., Kribbs, N. B., Morrison, A. R., Silver, S. M.& Mulvaney, F. D. (1994b). Motor dysfunction during sleep in posttraumatic stress disorder. Sleep, 17, 723–732.

    PubMed  Google Scholar 

  • Ross, R. J., Ball, W. A., Sullivan, K. A.,& Caroff, S. N. (1989). Sleep disturbance as the hallmark of posttraumatic stress disorder. American Journal of Psychiatry, 146, 697–707.

    PubMed  Google Scholar 

  • Schlosberg, A.,& Benjamin, M. (1978). Sleep patterns in three acute combat fatigue cases. Journal of Clinical Psychiatry, 39, 546–549.

    PubMed  Google Scholar 

  • Smith, C,& Lapp, L. (1991). Increases in number of REMs and REM density in humans following an intensive learning period. Sleep, 14, 325–330.

    PubMed  Google Scholar 

  • van der Kolk, B. A., Blitz, R., Burr, W. A., Sheery, S.,& Hartmann, E. (1984). Nightmares and trauma: A comparison of nightmares after combat with lifelong nightmares in veterans. American Journal of Psychiatry, 141, 187–190.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer Science+Business Media New York

About this chapter

Cite this chapter

Mellman, T.A. (2000). Sleep and the Pathogenesis of PTSD. In: Shalev, A.Y., Yehuda, R., McFarlane, A.C. (eds) International Handbook of Human Response to Trauma. Springer Series on Stress and Coping. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4177-6_21

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-4177-6_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6873-1

  • Online ISBN: 978-1-4615-4177-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics