Skip to main content

Dietary Intervention Studies of Colorectal Cancer

  • Chapter
Colon Cancer Prevention

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 470))

  • 181 Accesses

Abstract

This presentation will address three questions: 1) Why is dietary modification a viable strategy for preventing colorectal cancer? 2) Why are intervention studies an important component of cancer prevention research? 3) What is the current’ state of the evidence’ from dietary intervention studies of colorectal cancer?

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Zhao, L.P., Kushi, L.H., Klein, R.D., and Prentice, R.L. Quantitative review of studies of dietary fat and rat colon carcinoma. Nutr. Cancer 15:169–177, 1991.

    Article  PubMed  CAS  Google Scholar 

  2. Reddy, B.S. Diet and excretion of bile acids. Cancer Res. 41:3766–3768, 1981.

    PubMed  CAS  Google Scholar 

  3. Schatzkin, A., Schiffman, M., and Lanza, E. Research priorities in large bowel cancer prevention. Semin. Oncol. 17:425–437, 1990.

    PubMed  CAS  Google Scholar 

  4. Potter, J.D. Nutrition and colorectal cancer. Cancer Causes Control 7:127–146, 1996.

    Article  PubMed  CAS  Google Scholar 

  5. Wargovich, M.J. Precancer markers and prediction of tumorigenesis. In Young, G.P., Rozen, P., and Levin, B., eds. Prevention and early detection of colorectal cancer. Philadelphia: WB Saunders Company Ltd, 1996, pp. 89–101.

    Google Scholar 

  6. Fleming, T.R. and De Mets, D.L. Surrogate end points in clinical trials: are we being misled? Ann. Intern. Med. 125:605–613, 1996.

    PubMed  CAS  Google Scholar 

  7. Schatzkin, A., Freedman, L.S., Dawsey, S.M., and Lanza, E. Interpreting precursor studies: what polyp trials tell us about large bowel cancer. / Natl. Cancer Inst. 86:1053–1057, 1994.

    Article  CAS  Google Scholar 

  8. Bussey, H.J., De Cosse, J.J., Deschner, E.E., et al. A randomized trial of ascorbic acid in polyposis coli. Cancer 50:1434–1439, 1982.

    Article  PubMed  CAS  Google Scholar 

  9. De Cosse, J.J., Miller, H.H., and Lesser, M.L. Effect of wheat filer and vitamins C and E on rectal polyps in patients with familial adenomatous polyposis. J. Natl. Cancer Inst. 81:1290–1297, 1989.

    Article  Google Scholar 

  10. McKeown-Eyssen, G., Holloway, C., Jazmaji, V., Bright-See, E., Dion, P., and Bruce, W.R. A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps. Cancer Res. 48:4701–4705, 1988.

    PubMed  CAS  Google Scholar 

  11. Roncucci, L., DiDonato, P., Carati, L., et al. Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas. Dis. Colon Rectum 36:227–234, 1993.

    Article  PubMed  CAS  Google Scholar 

  12. Greenberg, E.R., Baron, J.A., Tosteson, T.D., et al. A clinical trial of antioxidant vitamins to prevent colorectal adenoma. New Engl J. Med. 331:141–147, 1994.

    Article  PubMed  CAS  Google Scholar 

  13. MacLennan, R., Macrae, E, Bain, C., et al. Randomized trial of intake of fat, fiber, and beta-carotene to prevent colorectal adenomas. / Natl. Cancer Inst. 87:1760–1766, 1995.

    Article  CAS  Google Scholar 

  14. Clark, L.C., Combs, G.E, and Turnbull, B.W. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial. JAMA 276:1957–1963, 1996.

    Article  PubMed  CAS  Google Scholar 

  15. Baron, J. Personal communication 1998.

    Google Scholar 

  16. Faivre, J., Doyon, F., and Boutron, M.C. For the European Cancer Prevention Colon Group. The ECP calcium fiber polyp prevention study. Eur. J. Cancer Prev. 1 (supplement 2):83–89, 1991.

    Google Scholar 

  17. Women’s Health Initiative Study Group. Design of the Women’s health Initiative Clinical Trial and Observational Study. Control. Clin. Trials 19:61–109, 1998.

    Article  Google Scholar 

  18. Martinez, M.E., Reid, M.E., Guillen-Rodrigues, J., et al. Design and baseline characteristics of study participants in the wheat bran fiber trial. Cancer Epidem. Biomarkers Prev. 7:813–816, 1998.

    CAS  Google Scholar 

  19. Burn, J., Chapman, P., and Eastham, E. A European double blind trial of aspirin and resistant starch in colon cancer prevention. Arch. Dis. Childhood 71:103–107, 1994.

    Article  CAS  Google Scholar 

  20. McKeown-Eyssen, G.E., Bright-See, E., Bruce, W.R., et al. A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps. J. Clin. Epidemiol. 47:525–536, 1994.

    Article  PubMed  CAS  Google Scholar 

  21. Schatzkin, A., Lanza, E., Freedman, L.S., Tangrea, J., Cooper, M.R., Iber, E, Selby, J., Caan, B., Weissfeld, J., Burt, R., Slattery, M., Kikendall, W., and Cahill, J. The Polyp Prevention Trial. I.: rationale, design, recruitment, and baseline participant characteristics. Cancer Epidemiol. Biomarkers Prev. 5:375–383, 1996.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer Science+Business Media New York

About this chapter

Cite this chapter

Schatzkin, A. (1999). Dietary Intervention Studies of Colorectal Cancer. In: Colon Cancer Prevention. Advances in Experimental Medicine and Biology, vol 470. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4149-3_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-4149-3_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6861-8

  • Online ISBN: 978-1-4615-4149-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics