Abstract
Due to more aggressive anti-cancer therapy in recent years, with thrombocytopenia as a principal side effect, the production of platelet concentrates (PC) by the American Red Cross Blood Services rose by 150% during the period from 1978 to 1988 [1]. Significantly less increase in production of RBC, only 24%, was seen during the same time period. As a result of the increased demand for platelets, there have been substantial efforts to make platelet transfusions more cost effective (i.e., to improve platelet yield and quality so that less units need to be transfused, while reducing the costs of processing and storage).
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References
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Holme, S. (1991). Platelet Function Preservation. In: Sibinga, C.T.S., Das, P.C., Mannucci, P.M. (eds) Coagulation and Blood Transfusion. Developments in Hematology and Immunology, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3900-1_7
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DOI: https://doi.org/10.1007/978-1-4615-3900-1_7
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