Skip to main content

Induction chemotherapy using intraarterial infusion

  • Chapter
Management of Gastric Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 55))

Abstract

Until recently gastrectomy was the only treatment offering any real prospect of cure for patients with gastric cancer. However, excepting patients with minimal disease, the results of gastrectomy alone have been unsatisfactory, whether the gastrectomy has been total or subtotal. Until recently the 5-year survival results of gastric resection in patients with invasive gastric cancer that appeared to be localized have variously been reported at between 5 and 25% [1–8]. Gastrectomy for patients with minimal disease, as detected from mass screening programs, has achieved better results [9]. However, in North America, Europe, and Australasia, patients with minimal disease form a small proportion of the overall numbers of patients with gastric cancer when first diagnosed [10].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Editorial, 1981. Med J Aust ••:402–403.

    Google Scholar 

  2. Fielding JWL, Ellis DJ, Jones BG, et al., 1980. Natural history of ‘early’ gastric cancer — results of a ten year regional survey. Br Med J 281:965–967.

    Article  PubMed  CAS  Google Scholar 

  3. Scott HW Jr., Adkins RB Jr., Sawyer JL, 1985. Results of an aggressive surgical approach to gastric carcinoma during a 23-year period. Surgery 97:55–59.

    PubMed  Google Scholar 

  4. Clark PI, Slevin ML, 1987. Chemotherapy for the stomach cancer. Br Med J 295:870–871.

    Article  CAS  Google Scholar 

  5. Salo JA, Saario I, Kivilaakso EO, et al., 1988. Near total gastrectomy for gastric cancer. Am J Surg 486–489.

    Google Scholar 

  6. Baddie AW, McBride CM, Batch CM, 1989. Gastric cancer. Am J Surg 157:595–606.

    Article  Google Scholar 

  7. Fielding JWL, 1988. The value of a multidisciplinary approach in the management of gastric cancer. Rec Results Ca Res 110:57–64.

    Article  CAS  Google Scholar 

  8. de Calan L, Portier G, Ozoux JP, et al., 1988. Carcinoma of the cardia and proximal third of the stomach. Results of surgical treatment in 91 consecutive patients. Am J Surg 155:481–485.

    Article  PubMed  Google Scholar 

  9. Miwa K, 1979. Cancer of the stomach in Japan. Gann Monograph on Cancer Research 22:61–75.

    Google Scholar 

  10. Milewski PJ, Bancewicz J, 1989. Improving the results of treating gastric cancer. Br Med 299:278–279.

    Article  CAS  Google Scholar 

  11. Okamura T, Tsujitani S, Korenaga D, et al., 1988. Lymphadenectomy for cure in patients with early gastric cancer and lymph node metastasis. Am J Surg 155:476–480.

    Article  PubMed  CAS  Google Scholar 

  12. Yamazaki H, Oshima A, Murakami R, et al., 1989. A long-term follow-up study of patients with gastric cancer detected by mass screening. Cancer 63:613–617.

    Article  PubMed  CAS  Google Scholar 

  13. Lehnert T, Sternberg S, Sprossmann M, De Cosse JJ, 1989. Early gastric cancer. Am J Surg 157:202–207.

    Article  PubMed  CAS  Google Scholar 

  14. Mine M, Maejima S, Harada M, Etani S, 1970. End results of gastrectomy for gastric cancer —effect of extensive lymph node dissection. Surgery 68:753–758.

    PubMed  CAS  Google Scholar 

  15. Moertel CG, Childs DS, O’Fallon JR, et al., 1984. Combined 5-FU and radiation therapy as a surgical adjuvant for poor prognosis gastric carcinoma. J Clin Oncol 2:1249–1254.

    PubMed  CAS  Google Scholar 

  16. Kimura T, Koyama Y, 1979. Preventive chemotherapy after radical operations in stomach cancer. In Advances in Medical Education, Vol. 9 (Thatcher N, ed). pp. 255–268.

    Google Scholar 

  17. Inokuchi K, Hattori T, Taguchi T, et al., 1984. Postoperative adjuvant chemotherapy for gastric carcinoma. Analysis of data of 1805 patients followed for 5 years. Cander 53:2393–2397.

    CAS  Google Scholar 

  18. Engstrom PF, Lavin PT, Douglass HO Jr., et al., 1985. Postoperative adjuvant 5-FU plus methyl CCNU therapy for gastric cancer patients. Eastern Cooperative Oncology Group Study (EST 3275) Cancer 55:1868–1873.

    PubMed  CAS  Google Scholar 

  19. Stephens FO, 1989. The case for a name change from neoadjuvant to induction chemotherapy (editorial). Cancer 63:1245–1246.

    Article  PubMed  CAS  Google Scholar 

  20. Shanta P, Krishnamurthi S, 1980. Combined bleomycin and radiotherapy in oral cancer. Clin Radiol 31:617–620.

    Article  PubMed  CAS  Google Scholar 

  21. Arcangeli G, Nervi C, Righini R, et al., 1983. Combined radiation and drugs: The effect of intra-arterial chemotherapy followed by radiotherapy in head and neck cancer. Radiother Oncol 1:101–107.

    Article  PubMed  CAS  Google Scholar 

  22. Stephens FO, 1989. Advanced breast cancer — primary intra-arterial induction chemotherapy. Reg Cancer Treat 2:5–8.

    Google Scholar 

  23. Ensminger WD, Gyves JW, 1984. Regional cancer chemotherapy. Ca Treat Rep 68:101–115.

    CAS  Google Scholar 

  24. Jaffe N, Robertson K, Takave Y, et al., 1985. Control of primary osteosarcoma with chemotherapy. Cancer 56:461–466.

    Article  PubMed  CAS  Google Scholar 

  25. Stephens FO, Marsden W, Tattersall MHN, 1989. Regional induction chemotherapy followed by radiotherapy and surgery in management of large and aggressive sarcomas. Reg Cancer Treat, in press.

    Google Scholar 

  26. Papaioannou AN, Kozanis JA, Polychronis AP, et al., 1986. Preoperative chemotherapy for gastric cancer. Rec Results Ca Res 103:142–147.

    Article  CAS  Google Scholar 

  27. Stephens FO, 1983. The pharmacokinetics of intra-arterial chemotherapy. Rec Results Ca Res 86:1–12.

    Article  CAS  Google Scholar 

  28. Stephens FO, Adams BG, Crea P, 1986. Intra-arterial chemotherapy given preoperatively in the management of carcinoma of the stomach. SG&O 162:370–374.

    CAS  Google Scholar 

  29. Fujimoto S, Akao T, Itoh B, et al., 1976. A study of survival in patients with stomach cancer treated by a combination of preoperative intra-arterial infusion therapy and surgery. Cancer 37:1648–1653.

    Article  PubMed  CAS  Google Scholar 

  30. Taguchi T, Nakamura H, 1989. In Arterial sInfusion Chemotherapy. Tokyo: Japan Journal Cancer and Chemotherapy Publications Inc., pp. 247–256.

    Google Scholar 

  31. Nakajima T, Takahashi T, Takagi K, et al., 1984. Comparison of 5-FU with ftorafur in adjuvant chemotherapies with combined inductive and maintenance therapies for gastric cancer. J Clin Oncol 2:1366–1379.

    PubMed  CAS  Google Scholar 

  32. Allum WH, Hallissey MT, Kelly KA, 1989. Adjuvant chemotherapy in operable gastric cancer. Lancet: 571–574.

    Google Scholar 

  33. Douglass HO Jr., 1985. Gastric cancer: Overview of current therapies. Semin Oncol 12(3)(Supple. 4):57–62.

    PubMed  Google Scholar 

  34. Sugarbaker PH, Cunliffe W, Belliveau JF, et al., 1988. Rationale for perioperative intra-peritoneal chemotherapy as a surgical adjuvant for gastrointestinal malignancy. Reg Cancer Treat 1:66–79.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer Science+Business Media New York

About this chapter

Cite this chapter

Stephens, F.O. (1991). Induction chemotherapy using intraarterial infusion. In: Sugarbaker, P.H. (eds) Management of Gastric Cancer. Cancer Treatment and Research, vol 55. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3882-0_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-3882-0_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6731-4

  • Online ISBN: 978-1-4615-3882-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics