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Measurement of Long-Term Effects of Oxidative Drug Metabolism in Erythrocytes

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Abstract

One of the well-known consequences of oxidative drug metabolism in erythrocytes is the increased production of oxidized glutathione (GSSG) (1). It has been shown by experiments in vitro that GSSG reacts with β–93-SH groups of hemoglobin (Hb) yielding the HbASSG derivative (2,3).

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References

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Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Science University of Belgrade, P.O. Box 550, Belgrade, YU-11001, Yugoslavia

    V. Niketic, O. Mitrasinovic, S. Jovanovic & N. Tomasevic

Authors
  1. V. Niketic
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  2. O. Mitrasinovic
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  3. S. Jovanovic
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  4. N. Tomasevic
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Editor information

Editors and Affiliations

  1. Case Western Reserve University, Cleveland, Ohio, USA

    Oddvar F. Nygaard

  2. New York University Medical Center, New York, USA

    Arthur C. Upton

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© 1991 Springer Science+Business Media New York

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Niketic, V., Mitrasinovic, O., Jovanovic, S., Tomasevic, N. (1991). Measurement of Long-Term Effects of Oxidative Drug Metabolism in Erythrocytes. In: Nygaard, O.F., Upton, A.C. (eds) Anticarcinogenesis and Radiation Protection 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3850-9_23

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  • DOI: https://doi.org/10.1007/978-1-4615-3850-9_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6718-5

  • Online ISBN: 978-1-4615-3850-9

  • eBook Packages: Springer Book Archive

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