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Tumor Suppressor Genes and the Age-Dependence of Cancer Incidence

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Anticarcinogenesis and Radiation Protection 2

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Abstract

The nature and number of events involved in the origin of cancer has been a subject of inquiry for many years. Ideas bearing on this subject derive from several sources, including human cancer incidences, experimental carcinogenesis in animals, hereditary cancer, and molecular genetic studies on cancers of both animals and humans. It is now appropriate to compare these ideas in an effort to understand the process of carcinogenesis.

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Author information

Authors and Affiliations

  1. Fox Chase Cancer Center, Philadelphia, PA, 19111, USA

    Alfred G. Knudson Jr.

Authors
  1. Alfred G. Knudson Jr.
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Editor information

Editors and Affiliations

  1. Case Western Reserve University, Cleveland, Ohio, USA

    Oddvar F. Nygaard

  2. New York University Medical Center, New York, USA

    Arthur C. Upton

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© 1991 Springer Science+Business Media New York

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Knudson, A.G. (1991). Tumor Suppressor Genes and the Age-Dependence of Cancer Incidence. In: Nygaard, O.F., Upton, A.C. (eds) Anticarcinogenesis and Radiation Protection 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3850-9_15

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  • DOI: https://doi.org/10.1007/978-1-4615-3850-9_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6718-5

  • Online ISBN: 978-1-4615-3850-9

  • eBook Packages: Springer Book Archive

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