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The Developing Gastrointestinal Tract and Milk-Borne Epidermal Growth Factor

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Immunology of Milk and the Neonate

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 310))

Abstract

In adult mammals, epidermal growth factor (EGF) is produced mainly in the submandibular and Brunner’s glands1–3. The production of EGF in suckling mammals is considered to be very low. Popliker et a1.4 reported absence of EGF mRNA in suckling mice; others described only very small amounts of EGF to be present in submandibular glands of suckling rodents1,5–7. EGF is known to play an important regulatory role in the mammals; many studies suggest that EGF is a trophic factor for various regions of the developing gastrointestinal tract8–17 and liver18,19.

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Author information

Authors and Affiliations

  1. Departments of Pediatrics and Physiology, University of Arizona, Tucson, AZ, USA

    Otakar Koldovský, John Britton, Diane Davis, Thomas Davis, Judy Grimes, Wuyi Kong, Radhakrishna Rao & Paul Schaudies

  2. Walter Reed Army Medical Center, Washington, DC, USA

    Paul Schaudies

Authors
  1. Otakar Koldovský
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  2. John Britton
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  3. Diane Davis
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  4. Thomas Davis
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  5. Judy Grimes
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  6. Wuyi Kong
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  7. Radhakrishna Rao
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  8. Paul Schaudies
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky

  2. National Institutes of Health, Bethesda, Maryland, USA

    Claudia Blair

  3. University of Texas, Galveston, Texas, USA

    Pearay L. Ogra

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© 1991 Springer Science+Business Media New York

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Koldovský, O. et al. (1991). The Developing Gastrointestinal Tract and Milk-Borne Epidermal Growth Factor. In: Mestecky, J., Blair, C., Ogra, P.L. (eds) Immunology of Milk and the Neonate. Advances in Experimental Medicine and Biology, vol 310. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3838-7_11

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  • DOI: https://doi.org/10.1007/978-1-4615-3838-7_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6713-0

  • Online ISBN: 978-1-4615-3838-7

  • eBook Packages: Springer Book Archive

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