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Abnormal Fibrinogens with Two Structural Defects

  • Michio Matsuda
  • Shigeharu Terukina
  • Nobuhiko Yoshida
  • Kensuke Yamazumi
  • Hisato Maekawa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 281)

Abstract

Among the abnormal fibrinogens which we recently analyzed, two types of abnormality were found to have two structural defects: a genetically determined amino acid substitution and an additional secondary modification of the molecule due to the mutation (1, 2). Here we briefly describe these abnormal molecules.

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Michio Matsuda
    • 1
  • Shigeharu Terukina
    • 1
  • Nobuhiko Yoshida
    • 1
  • Kensuke Yamazumi
    • 1
  • Hisato Maekawa
    • 1
  1. 1.Institute of HematologyJichi Medical SchoolTochigi-KenJapan

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