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Thrombin-Like Venom Enzymes: Structure and Function

  • Hubert Pirkle
  • Ida Theodor
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 281)

Abstract

While thrombin itself has an ever-growing number of reported biochemical and biological actions, the term thrombin-like enzyme usually connotes only one of these actions—the ability to induce the clotting of fibrinogen. The phylogenetic and developmental distance between mammalian thrombin and the thrombin-like enzymes of snake venoms provides opportunities for comparative studies on the structural requirements for their highly specific coagulant actions on fibrinogen.

Keywords

Snake Venom Bovine Thrombin Animal Venom Venom Enzyme Pacific Rattlesnake 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Hubert Pirkle
    • 1
  • Ida Theodor
    • 1
  1. 1.Department of Pathology College of MedicineUniversity of California, IrvineUSA

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