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Paramyxovirus M Proteins

Pulling It All Together and Taking It on the Road

  • Chapter
The Paramyxoviruses

Part of the book series: The Viruses ((VIRS))

Abstract

The paramyxovirus M protein has the job of gathering all of the virus components together at the plasma membrane in preparation for budding. It is a prototype for performing the assembly “bandleader” function: a function which all enveloped viruses must perform. While the paramyxovirus M protein is clearly involved in this orchestration, the mechanisms by which it functions are far from clear. In addition, assembly may not be the only role played by the M protein. The M protein may be involved in regulating another viral function, transcription. Furthermore, the striking localization of the M protein of one paramyxovirus, Newcastle disease virus (NDV), to the nucleus of infected cells may imply another, as yet unknown, function for the M protein.

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  1. Department of Immunology/Microbiology, Rush Medical College, Chicago, Illinois, 60612, USA

    Mark E. Peeples

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  1. Howard Hughes Medical Institute, Bethesda, Maryland, USA

    David W. Kingsbury

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© 1991 Springer Science+Business Media New York

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Peeples, M.E. (1991). Paramyxovirus M Proteins. In: Kingsbury, D.W. (eds) The Paramyxoviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3790-8_16

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  • DOI: https://doi.org/10.1007/978-1-4615-3790-8_16

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