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New Frontiers Opened by the Exploration of Host Cell Receptors

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The Paramyxoviruses

Part of the book series: The Viruses ((VIRS))

Abstract

The term virus receptor as used in this chapter is defined as a macromolecule or complex of macromolecules naturally occurring on the host cell surface which specifically binds the virus and through this binding facilitates the subsequent events of infection (Markwell et al., 1984b). The specificity of the recognition between the viral binding protein and its cellular receptor and the involvement of the biological process of infection are the two key elements of the definition.

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References

  • Burnet, F. M., and Lind, P. E., 1950, Haemolysis by Newcastle disease virus II. General character of hemolytic action, Aust. J. Exp. Biol. Med. 28:129–150.

    Article  CAS  Google Scholar 

  • Chanock, R. M., Kim, H. W., Brandt, C. D., and Parrott, R. H., 1982, in “Viral Infections of Humans: Epidemiology and Control,” (A. S. Evans, ed.), pp. 471–489, Plenum Press, New York.

    Chapter  Google Scholar 

  • Choppin, P. W., and Scheid, A., 1980, The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses, Rev. Infect. Dis. 2:40–61.

    Article  PubMed  CAS  Google Scholar 

  • Choppin, P. W., Klenk, H.-D., Compans, R. W., and Caliguiri, L. A., 1971, The parainfluenza virus SV5 and its relationship to the cell membrane, Perspect. Virol. VII: 127–158.

    Google Scholar 

  • Cuatrecasas, P., 1973, Interaction of Vibrio cholerae enterotoxin with cell membranes, Biochemistry 12:3558–3566.

    Article  PubMed  CAS  Google Scholar 

  • Cumar, F. A., Maggio, B., and Caputo, R., 1978, Dopamine release from nerve endings induced by polysialogangliosides, Biochem. Biophys. Res. Commun. 84:65–69.

    Article  PubMed  CAS  Google Scholar 

  • Demel, R. A., Sehgal, P. B., and Landsberger, F. R., 1987, A structural model for fusion of viral and cellular membranes, in “The Biology of Negative Strand Viruses” (B. Mahy and D. Kolakofsy, eds.), pp. 26–32, Elsevier Science Publishers, New York.

    Google Scholar 

  • Dimpfel, W., Huang, R. T. C., and Habermann, E., 1977, Gangliosides in nervous tissue cultures and binding of 125I-labeled tetanus toxin, a neuronal marker, J. Neurochem. 29:329–334.

    Article  PubMed  CAS  Google Scholar 

  • Fan, D. P., and Sefton, B. M., 1978, The entry into host cells of Sindbis virus, vesicular stomatitis virus and Sendai virus, Cell 15:985–992.

    Article  PubMed  CAS  Google Scholar 

  • Feldman, H. A., 1976, Mumps, in “Viral Infections of Humans: Epidemiology and Control” (A. S. Evans, ed.), pp. 317–336, Plenum Press, New York.

    Chapter  Google Scholar 

  • Fishman, P. H., Moss, J., and Vaughan, M., 1976, Uptake and metabolism of gangliosides in transformed mouse fibroblasts, J. Biol. Chem. 251:4490–4494.

    PubMed  CAS  Google Scholar 

  • Gingell, D., and Ginsberg, L., 1978, Problems in the physical interpretation of membrane interaction and fusion, in “Membrane Fusion” (G. Poste and G. L. Nicolson, eds.), pp. 791–833, North Holland, New York.

    Google Scholar 

  • Glezen, W. P., Frank, A. L., Taber, L. H., and Kasel, J. A., 1984, Parainfluenza virus type 3: Seasonality and risk of infection and reinfection in young children, J. Infect. Dis. 150:851–857.

    Article  PubMed  CAS  Google Scholar 

  • Haferkamp, G., 1987, Present state of clinical experience of ganglioside application in man, in “Gangliosides and Modulations of Neuronal Functions” (H. Rahmann, ed.), pp. 573–580, Springer-Verlag, Berlin.

    Chapter  Google Scholar 

  • Haff, R. F., and Stewart, R. C., 1964, Role of sialic acid receptors in adsorption of influenza virus to chick embryo cells, J. Immunol. 94:842–851.

    Google Scholar 

  • Harrowe, G., Mitsuhashi, M., and Payan, D. G., 1990, Measles virus-substance P receptor interactions: Possible novel mechanism of viral fusion, J. Clin. Invest. 85:1324–1327.

    Article  PubMed  CAS  Google Scholar 

  • Haywood, A. M., 1974, Characteristics of Sendai virus receptors in a model membrane, J. Mol. Biol. 83:427–436.

    Article  PubMed  CAS  Google Scholar 

  • Haywood, A. M., 1975, Model membranes and Sendai virus surface-surface interactions, in “Negative Strand Viruses,” Vol. 2 (W. J. Mahy and R. D. Barry, eds.), pp. 923–928, Academic Press, New York.

    Google Scholar 

  • Haywood, A. M., and Boyer, B. P., 1982, Sendai virus membrane fusion: Time course and effect of temperature, pH, calcium and receptor concentration, Biochemistry 21:6041–6046.

    Article  PubMed  CAS  Google Scholar 

  • Herrler, G., and Klenk, H.-D., 1987a, Restoration of receptors for influenza C virus on chicken erythorcytes by incorporation of bovine brain gangliosides, in “The Biology of Negative Strand Viruses” (B. Mahy and D. Kolakofsky, eds.), pp. 63–67, Elsevier, New York.

    Google Scholar 

  • Herrler, G., and Klenk, H.-D., 1987b, The surface receptor is a major determinent of the cell tropism of influenza C virus, Virology 159:102–108.

    Article  PubMed  CAS  Google Scholar 

  • Holmgren, J., Elwing, H., Fredman, P., and Svennerholm, L., 1980a, Polystyrene-adsorbed gangliosides for investigation of the structure of the tetanus toxin receptor, Eur. J. Biochem. 106:371–379.

    Article  PubMed  CAS  Google Scholar 

  • Holmgren, J., Svennerholm, L., Elwing, H., Fredman, P., and Stannegard, O., 1980b, Sendai virus receptor: Proposed recognition based on binding to plastic-adsorbed gangliosides, Proc. Nail. Acad. Sci. USA 77:1947–1950.

    Article  CAS  Google Scholar 

  • Homma, M., and Ohuchi, M., 1973, Trypsin action on the growth of Sendai virus in tissue culture cells. III. Structural difference of Sendai viruses grown in eggs and tissue culture cells, J. Virol. 12:1457–1465.

    PubMed  CAS  Google Scholar 

  • Howe, C., and Lee, L. T., 1972, Virus-erythrocyte interactions, Adv. Virus Res. 17:1–50.

    Article  PubMed  CAS  Google Scholar 

  • Huang, R. T. C., Rott, R., and Klenk, H.-D., 1973, On the receptor of influenza viruses 1. Artificial receptor for influenza virus, Z. Naturforsch 28c:342–345.

    Google Scholar 

  • Ito, Y., Yamamoto, F., Takano, M., Maeno, K., Shimokata, K., Iinuma, M., Hara, K., and Iijima, S., 1982, Comparative studies on the distribution mode of orthomyxo-virus and paramyxo-virus receptor possessing cells in mice and birds, Med. Microbiol. Immunol. 171:59–68.

    Article  PubMed  CAS  Google Scholar 

  • Ito, Y., Yamamoto, F., Takano, M., Maeno, K., Shimokata, K., Iinuma, M., Hara, K., and Iijima, S., 1983, Detection of cellular receptors for Sendai virus in mouse tissue sections, Arch. Virol. 75:103–113.

    Article  PubMed  CAS  Google Scholar 

  • Jakab, G. J., 1984, Viral-bacterial interactions in respiratory infections: A review of the mechanisms of virus-induced suppression of pulmonary antibacterial defenses, in “Bovine Respiratory Disease” (R. W. Loan, ed.), pp. 223–286, Texas A&M University Press, College Station, Texas.

    Google Scholar 

  • Jaques, L. W., Brown, E. B., Barrett, J. M., Wallace, Jr., S. B., and Weltner, Jr., W., 1977, Sialic acid: A calcium binding carbohydrate, J. Biol. Chem. 252:4533–4538.

    PubMed  CAS  Google Scholar 

  • Kingsbury, D. W., Bratt, M. A., Choppin, P. W., Hanson, R. P., Hosaka, Y., ter Meulen, V., Norrby, E., Plowright, W., Rott, R., and Wunner, W. H., 1978, Paramyxoviridae, Intervirology 10:137–15

    Article  Google Scholar 

  • Koscielak, J., Hakomori, S.-I., and Jeanloz, R. W., 1968, Glycolipid antigen and its antibody, Immunochemistry 5:441–455.

    Article  CAS  Google Scholar 

  • Krah, D. L., 1989, Characterization of octyl glucoside-solubilized cell membrane receptors for binding measles virus, Virology 172:386–390.

    Article  PubMed  CAS  Google Scholar 

  • Krah, D. L., and Choppin, P. W., 1988, Mice immunized with measles virus develop antibodies to a cell surface receptor for binding virus, J. Virol. 62:1565–1572.

    PubMed  CAS  Google Scholar 

  • Maggio, B., and Lucy, J. A., 1976, Polar-group behavior in mixed monolayers of phospholipids and fusogenic lipids, Biochem. J. 155:353–364.

    PubMed  CAS  Google Scholar 

  • Maggio, B., Cumar, F. A., and Capulto, R., 1978, Induction of membrane fusion by poly-sialogangliosides, FEBS Lett. 90:149–152.

    Article  PubMed  CAS  Google Scholar 

  • Marcus, P. I., 1959, Symposium on the biology of cells modified by viruses or antigens IV. Single-cell techniques in tracing virus-host interactions, Bacteriol. Rev. 23:232–249.

    PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., 1986, Viruses and hemagglutinins and lectins, in “Microbial Lectins and Agglutinins” (D. Mirelman, ed.), pp. 21–53, Wiley, New York.

    Google Scholar 

  • Markwell, M. A. K., and Fox, C. F., 1980, Protein-protein interactions within paramyxoviruses identified by native disulfide bonding or reversible chemical cross-linking, J. Virol. 33:152–166.

    PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., and Paulson, J. C., 1980, Sendai virus utilizes specific sialyloligosaccharides as host cell receptor determinants, Proc. Natl. Acad. Sci. USA 77:5693–5697.

    Article  PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., and Sato, E., 1987, Receptor gangliosides identified in target tissue for Sendai virus, in “Glycoconjugates: Proceedings of the 9th International Symposium” (J. Montreuil, A. Verbert, G. Spik, and B. Fournet, eds.), p. G33, A. Lerouge, Tourcoing, France.

    Google Scholar 

  • Markwell, M. A. K., Svennerholm, L., and Paulson, J. C., 1981, Specific gangliosides function as host cell receptors for Sendai virus, Proc. Natl. Acad. Sci. USA 78:5406–5410.

    Article  PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., Fredman, P., and Svennerholm, L., 1984a, Specific gangliosides are receptors for Sendai virus, Adv. Exp. Biol. 174:369–379.

    Article  CAS  Google Scholar 

  • Markwell, M. A. K., Fredman, P., and Svennerholm, L., 1984b, Receptor ganglioside content of three hosts for Sendai virus: MDBK, HeLa, and MDCK Cells, Biochim. Biophys. Acta 775:7–16.

    Article  PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., Portner, A., and Schwartz, A., 1985, An alternative route of infection for viruses: Entry by means of the asialoglycoprotein receptor of a Sendai virus mutant lacking its attachment protein, Proc. Natl. Acad. Sci. USA 82:978–982.

    Article  PubMed  CAS  Google Scholar 

  • Markwell, M. A. K., Moss, J., Hom, B. E., Fishman, P. H., and Svennerholm, L., 1986, Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus, Virology 155:356–364.

    Article  PubMed  CAS  Google Scholar 

  • Marsh, M., 1982, The entry of enveloped viruses into cells by endocytosis, Biochem. J. 218:1–10.

    Google Scholar 

  • Matlin, K. S., Reggio, H., Helenius, A., and Simons, K., 1981, Infectious entry pathways of influenza virus in a canine kidney line, J. Cell Biol. 91:601–613.

    Article  PubMed  CAS  Google Scholar 

  • Peeples, M. E., 1988, Newcastle disease virus replication, in “Newcastle Disease” (D. J. Alexander, ed.), pp. 45–78, Kluwer Academic Publishers, Boston.

    Chapter  Google Scholar 

  • Peters, M. W., Singleton, C., Barber, K. R., and Grant, C. W. M., 1983, Glycolipid crypticity in membranes—Not a simple shielding effect of macromolecules, Biochim. Biophys. Acta 731:475–482.

    Article  PubMed  CAS  Google Scholar 

  • Richardson, C. D., Scheid, A., and Choppin, P. W., 1981, Specific inhibition of paramyxovirus replication by hydrophobic oligopeptides, in “The Replication of Negative Strand Viruses” (D. H. L. Bishop and R. W. Compans, eds.), pp. 509–515, Elsevier/North-Holland, New York.

    Google Scholar 

  • Schauer, R., 1982, Chemistry, metabolism, and biological functions of sialic acids, Adv. Car-bohydr. Chem. Biochem. 40:131–234.

    Article  CAS  Google Scholar 

  • Scheid, A., and Choppin, P. W., 1974, The hemagglutinating and neuraminidase protein of a paramyxovirus: Interaction with neuraminic acid in affinity chromatography, Virology 62:125–133.

    Article  PubMed  CAS  Google Scholar 

  • Schroeder, C., 1986, Substance P, a neuropeptide, inhibits measles virus replication in cell culture, Acta Virol. 30:432–435.

    PubMed  CAS  Google Scholar 

  • Sharom, F. J., and Grant, C. W. M., 1978, A model for ganglioside behavior in cell membranes, Biochim. Biophys. Acta 507:208–293.

    Google Scholar 

  • Sharom, F. J., Barratt, D. G., Thede, A. E., and Grant, C. W. M., 1976, Glycolipids in model membranes: Spin-label and freeze-etch studies, Biochim. Biophys. Acta 455:485–492.

    Article  PubMed  CAS  Google Scholar 

  • Stein, K. E., Schwarting, G. A., and Marcus, D. M., 1978, Glycolipid markers of murine lymphocyte subpopulations, J. Immunol. 120:676–679.

    PubMed  CAS  Google Scholar 

  • Stone, J. D., 1948, Prevention of virus infection with enzyme of V. cholerae I. Studies with viruses of mumps-influenza group in chick embryos, Aust. J. Exp. Biol. Med. Sci. 26:49–64.

    Article  PubMed  CAS  Google Scholar 

  • Storey, D. G., Coté, M.-J., Dimock, K., and Kang, C. Y., 1987, Nucleotide sequence of the coding and flanking regions of the human parainfluenza virus 3 hemagglutinin-neuraminidase gene: Comparison with other paramyxoviruses, Intervirology 27:69–80.

    Article  PubMed  CAS  Google Scholar 

  • Suzuki, Y., Suzuki, T., Matsunaga, M., and Matsumoto, M., 1985, Gangliosides as paramyxovirus receptor. Structural requirement of sialo-oligosaccharides in receptors for hemagglutinating virus of Japan (Sendai virus) and Newcastle disease virus, J. Biochem. 97:1189–1199.

    PubMed  CAS  Google Scholar 

  • Takamizawa, K., Iwamori, M., Kozaki, S., Sakaguchi, G., Tanaka, R., Takayama, H., and Nagai, Y., 1986, TLC immunostaining of Clostridium botulinum type A neurotoxin binding to gangliosides and free fatty acids, FEBS Lett. 201:229–232.

    Article  PubMed  CAS  Google Scholar 

  • Tashiro, M., and Hommas, M., 1983a, Pneumotropism of Sendai virus in relation to protease-mediated activation in mouse lungs, Infect. Immun. 39:879–888.

    PubMed  CAS  Google Scholar 

  • Tashiro, M., and Homma, M., 1983b, Evidence of proteolytic activation of Sendai virus in mouse lung, Arch. Virol. 77:127–137.

    Article  PubMed  CAS  Google Scholar 

  • Tashiro, M., Pritzer, E., Khoshnan, M. A., Yamakawa, M., Kuroda, K., Klenk, H.-D., Rott, R., and Seto, J. T., 1988, Characterization of a pantropic variant of Sendai virus derived from a host range mutant, Virology 165:577–583.

    Article  PubMed  CAS  Google Scholar 

  • Walsh, E. E., and Hruska, J., 1983, Monoclonal antibodies to respiratory syncytial virus proteins: Identification of the fusion protein, J. Virol. 47:171–177.

    PubMed  CAS  Google Scholar 

  • Wassilewa, L., 1977, Cell receptors for paramyxoviruses, Arch. Virol. 54:299–305.

    Article  PubMed  CAS  Google Scholar 

  • Whatley, R., Ng, S. K.-C., Roger, J., McMurray, W. C., and Sanwal, B. D., 1976, Developmental changes in gangliosides during myogenesis of a rat myoblast cell line and its drug resistant variants, Biochem. Biophys. Res. Commun. 70:180–185.

    Article  PubMed  CAS  Google Scholar 

  • Umeda, M., Nojima, S., and Inoue, K., 1984, Activity of human erythrocyte gangliosides as a receptor to HVJ, Virology 133:172–182.

    Article  PubMed  CAS  Google Scholar 

  • Van Heyningen, S., 1976, Binding of ganglioside by the chains of tetanus toxin, FEBS Lett. 68:5–7.

    Article  PubMed  CAS  Google Scholar 

  • Yamakawa, T., and Nagai, Y., 1978, Glycolipids at the cell surface and their biological functions, Trends Biochem. Sci. 3:128–131.

    Article  CAS  Google Scholar 

  • Yasuda, Y., Hosaka, Y., Fukami, Y., and Fukai, K., 1981, Immunoelectron microscopic study on interactions of noninfectious Sendai virus and murine cells, J. Virol. 39:273–281.

    PubMed  CAS  Google Scholar 

  • Yoshimura, A., Kuroda, K., Kawasaki, K., Yamashina, S., Maeda, T., and Ohnishi, S., 1982, Infectious cell entry mechanism of influenza virus, J. Virol. 43:284–293.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Section on Molecular Pharmacology, Clinical Neuroscience Branch, National Institute of Mental Health, Bethesda, Maryland, 20892, USA

    Mary Ann K. Markwell

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  1. Mary Ann K. Markwell
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  1. Howard Hughes Medical Institute, Bethesda, Maryland, USA

    David W. Kingsbury

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Markwell, M.A.K. (1991). New Frontiers Opened by the Exploration of Host Cell Receptors. In: Kingsbury, D.W. (eds) The Paramyxoviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3790-8_15

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  • DOI: https://doi.org/10.1007/978-1-4615-3790-8_15

  • Publisher Name: Springer, Boston, MA

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