Abstract
In all mammals tested so far melatonin (MT), the main pineal hormone, is secreted according to a large-amplitude circadian rhythm. Its profile of secretion is characterized by a brisk surge during the period of darkness with the peak in the first hours after midnight and decline before dawn; during the day-light hours serum MT concentrations are persistently low (Preslock,1984).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abe, H., Engler, D., Molitch, M.E., Bollinger-Cruber, J., Reichlin, S., 1985, Vasoactive intestinal peptides is a physiological mediator of prolactin release in the rat. Endocrinology, 116:1383
Angeli, A., Dogliotti, L., Orlandi, F., Muccioli, G.P., Bellussi, G., Di Carlo, R., 1986, The dopaminergic system and breast disease: novel approaches to pathophysiology and treatment. in “Endocrinology 85” Molinatti, G.M., Martini, L., eds. Elsevier, New York
Anton-Tay, F., Chou, C., Anton, S., Wurtman, R.J., 1986, Brain serotonin concentrations: elevation following intraperitoneal administration of melatonin. Science, 162:277–278
Arendt, J., 1988, Melatonin. Clin Endocrinol, 29:205–229
Arendt, J., Borbely, A. A., Franey, C., Wright, J., 1984, The effect of chronic, small doses of melatonin given in the late afternoon on fatigue in man: a preliminary study. Neurosci Letters, 45:317–321
Arey, I.J., Averill, R.L.W., Freeman, M.E., 1989, Sex specific endogenous stimulatory rhythm regulating prolactin secretion. Endocrinology, 124:119–123
Bartsch, C., Bartsch, H., Fuchs, U., Lippert, T.H., Bellman, O., Gupta D., 1989, Stage-dependent depression of melatonin in patients with primary breast cancer. Cancer 64:426–433
Ben-Jonathan, N., 1985, Dopamine: A prolactin-inhibiting hormone. Endocrin Rev, 6: 564–589
Bhatavdekar, J.M., Shang, N.G., Giri, D.D., Karelia N.H., Trivedi, S.N., Vora H.H., Patel D.D., 1990, Plasma prolactin as a tumor marker in advanced breast cancer. in 2nd international symposium on hormonal manipulation of cancer, (abs n. 123), Rotterdam 1990
Bispink, G., Zimmermann, R., Weise, H.C., Leidenberger, F., 1990, Influence of melatonin on the sleep-independent component of prolactin secretion, J Pineal Res, 8:97–105
Bittman, E.L., Kaynard, A.H., Olsten, D.H., Robison, J.E., Yellon, S.M., Karsch, F.S., 1985, Pineal melatonin mediates photoperiodic control of pulsatile luteizing hormone secretion in the ewe. Neuroendocrinology, 40:418–419
Brezinski, A., Wurtman, R.J., 1988, The pineal gland: its possible role in human reproduction. Obstetric Gynecol Surv, 43:197–207
Brezinski, A., Lynch, H.J., Wurtman, R.J., 1987, Possible contribution of melatonin to the timing of the luteinizing hormone surge. N Engl J Med, 316:1550–1551
Capelli, M., Valastro, G.F., Filicori, M., 1988, Automazione nel laboratorio di endocrinologia. in “Bioritmi endocrini: fisiologia, diagnostica ed applicazioni terapeutiche.” Filicori M., Flamigni C., Crowley F., eds, CIC.Edizioni Internazionali, Roma
Carandente, F., Angeli, A., Candiani, G.B., Crosignani, P.G., Dammacco, F., De Cecco, L., Marrama, P., Massobrio, M., Martini, L., 1989, Rhythms in the ovulatory cycle. 1st: prolactin, Chronobiologia, 16 35–44
De Leiva, A., Tortosa, F., Peinado, M.A., Serrano, J., Rodriguez-Espinosa, J., Puig-Domingo, M., 1990, Episodic secretion of melatonin in adult humans: lack of a relation with a LH pulse pattern.Acta Endocrin, 122:76–82
Dogliotti, L., Torta, M., Berruti, A., Buniva, T., Terzolo, M., Faggiuolo, R., 1987, Melatonin relationship to human tumors. in “The pineal gland and cancer.” D. Gupta, A. Attanasio, R. J., Reiter eds, Brain Research Promotion, Tubingen.
Dowsett, M., Mc Garrick, A.L., Harris, A.L., Coombes, R.J., Smith, I.E., Jeffcoate, S.E., 1983, Prognostic significance of serum prolactin levels in advanced breast cancer. Br J Cancer, 34:323–328
Fideleff, H., Aparico, N.J., Guitelman, A., 1976, Effects of melatonin on basal and stimulated gonadotropins levels in normal men and postmenopausal women. J Clin Endocrin Metab, 42:1014–1017
Haus, E., Lakatua, D.J., Halberg, F., Halberg E., 1980, Chronobiological studies of plasma prolactin in women in Kyushu, Japan and Minnesota. J Clin Endocrin Metab, 51:632–40
Holtkamp, W., Nagel, G.E., Wander, H.E., Rauschenker H.F., Von Heyden, D., 1984, Hyperprolactinemia is an indicator of progressive disease and poor prognosis in advanced breast cancer.Int J Cancer, 34:323–328
Kamberi, I.A., Mical, R., Porter, J.C., 1971, Effects of melatonin and serotonin on the release of FSH and prolactin. Endocrinology. 88: 1288–1293
Kauppila, A., Kivela, A., Pakarinen, A., Vakkuri, O., 1987, Inverse seasonal relatioship between melatonin and ovarian activity in humans in a region with a strong seasonal contrast in luminosity. J Clin Endocrinol Metab, 65:823–828
Kordon, C., Blake, C.A., Terkel, J., Sawyer C.H., 1973, Partecipation of serotonin-containing neurons in the suckling-induced rise in plasma prolactin levels during stress in male rats. Neuroendocrinology,13:213–223
Lissoni, P., Resentini, M., Mayri, R., De Medici, C., Morabito, F., Esposti, D., Di Bella, L., Esposti, G., Rossi, D., Parravicini, L, Legname, G., Fraschini, F., 1986, Effect of an acute injection of melatonin on the basal secretion of hypophyseal hormones in prepubertal and pubertal healthy subjects. Acta Endocrin, 111:305–311
Malarkey, W.B., Schroeder, L.L., Stevens, V.C., James, A.G., Lanese R.R., 1977, Disordered nocturnal prolactin regulation in women with breast cancer. Cancer Res, 7:4650–4654
MacLeod, R.M., Cronin, M.J., Valdenegro, C.A., Login, I.S., Thorner, M.O., 1980, Neural and ovarian regulation of prolactin production. In“ Progress in Psychoneuroendocrinology.” Brambilla, F., Racagni, G., De Wierd, D. eds. Elsevier, Amsterdam
Mallo, C., Zaidan, R., Faure, A., Brun, C.J., Claustrat, B., 1988, Effect of a four-day nocturnal melatonin treatment on the 24 h plasma melatonin, cortisol and prolactin profiles in humans. Acta Endocrinologica, 119:474–480
Melzer, H.J., Fang, V.S., Daniels, S., 1976, Biogenic amines and serum prolactin levels during stress in male rats. Fed Proc Fed Am Soc Exp Biol, 35:554
Nordlund, J., Lerner, A., 1977, The effect of oral melatonin on skin color and the release of pituitary hormones. J Clin Endocrinol Metab, 54:768–774
Pohl, C.R., Weiner, R.I., Smith, M.S., 1985, Concordance between LH and PRL pulse in ovariectomized rats in the presence and absence of dopamine inhibition. (abs n. 95) in 1st International Congress of Neuroendocrinology, S: Francisco, California
Preslock, J.P., 1984, The pineal gland: basic implications and clinical correlations. Endocrine Rev., 5: 282–308
Reichlin, S., Molitch, M., 1984, Neuroendocrine aspects of pituitary adenoma In “Pituitary hyperfunction”, Camanni F, Muller E.E., eds, Raven Press, New York
Reid, R.L., Hoff, J.D., Yen, S., Li, C.H., 1981, Effects of exogenous ß-endorphin on pituitary hormone secretion and its disappearance rate in normal human subjects. J Clin Endocrinol Metabol, 52:1179–1184
Smith, M.S., Pohol, C.R., Weiner, R.I., 1986, Evidence for hypothalamic regulation of pulsatile prolactin secretion in the rat. in 16th Annual meeting of the society for Neuroscience, Washington, DC
Strassmann, R.J., Peake, G.T., Qualls, C.R., Lisansky, E.J., 1987, A model for the study of the acyte effects of melatonin in man. J Clin Endocrinol Metabol, 65:842–47
Swearinger, K.C., Nicoll, C., 1972, Prolactin turnover in rat adenohypophysis in vivo: its evaluation as a method for estimating secretion rates. J Endocrinol, 53:1
Tamarkin, L., Baird, C., Almeida, O.F.X., 1985, Melatonin: a coordinating signal for mammalian reproduction? Science, 227:714–720
Wang, D.Y., Sturzaker, H.E., Kwa, H.G., Verhofstadt, F., Hayward, J.L., Bulbrook, 1984, Relationship between number of pregnancy and PRL levels, Int J Cancer, 33:629–633
Vakkuri, O., Leppaluoto, J., Kauppila, A., 1985, Oral administration and distribution of melatonin in human serum, saliva and urine. Life Sci, 37:489–495
Vaughan, G.M., Bell, R., De La Pena, A., 1979, Nocturnal plasma melatonin in humans: episodic pattern and influence of light. Neurosci Lett, 14: 81
Vaughan, M.K., Little, J.C., Johnson, L.J., 1978, Effects of melatonin and analogues of arginine vasotocine on plasma prolactin levels in adult male rats. Hormone Res, 9:236
Waldhauser, F., Liebermann, H.R., Lynch, H.J., 1987, Pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. Neuroendocrinology, 46:125
Waldhauser, F., Waldhauser, M., Liebermann, H.R., Deng, M.-H., Lynch, H.J., Wurtman, R.J., 1984, Bioavalaibility of oral melatonin in humans. Neuroendocrinology, 39:307–313
Webley, G.E., Lenton, E.A., 1987, The temporal relationship between melatonin and prolactin in women. Fertil Steril, 48:218–222
Weinberg, Y., Weitzman, E.D., Fukushima, D.K., 1980, Melatonin does not suppress the pituitary luteinizing hormone to luteinizing hormone-releasing hormone in men. J Clin Endocrin Metabol, 51:161–162
Welsh, C.W., 1985, Host factor affecting the growth of carcinogen induced rat mammary carcinomas. Cancer Res,45:3415–3443
Welsh, C.W., De Itturi, C., Brennan, M., 1976, Dna synthesis of human, mouse and rat mammary carcinomas in vitro,Cancer, 38:1272–1281
Wright, J., Aldhous, M., Franey, C., English, J., Arendt, J., 1986, The effect of exogenous melatonin on endocrine function in man. Clin Endocrinol, 24:375–381
Yen, S.S.C., Ehara, Y., Siler,T.M., 1974, Augmentation of prolactin secretion by estrogen in hypogonadal women. J Clin Endocrin Metab, 53:652–655
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media New York
About this chapter
Cite this chapter
Angeli, A. et al. (1991). Evidence for a Sex-Specific Facilitatory Effect of Melatonin on Prolactin Secretion. Is Pineal-Prolactin Interaction Relevant to the Clinical Course of Breast Cancer?. In: Fraschini, F., Reiter, R.J. (eds) Role of Melatonin and Pineal Peptides in Neuroimmunomodulation. NATO ASI Series, vol 204. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3756-4_30
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3756-4_30
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6673-7
Online ISBN: 978-1-4615-3756-4
eBook Packages: Springer Book Archive