Abstract
Cumulative epidemiological evidence suggests that exposure to solar radiation plays an important role in the pathogenesis of cutaneous malignant melamona (CM) (Kopf et al. 1984). This evidence is derived primarily from the fact that CM is most frequent in fair-skinned, red-haired persons who tend to freckle, burn easily, and tan poorly following exposure to sunlight. Direct experimental evidence that CM is correlated with increased susceptibility to skin injury induced by ultraviolet radiation (UVR) is rather limited.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Azizi, E., Lusky, A., Kushelevsky, A.P., and Schewach-Millet, M., 1988, Skin type, hair color and freckles are predictors of decreased minimal erythema UV-radiation dose. Journal of the American Academy of Dermatology, 19:32–38.
Azizi, E., Wax, Y., Lusky, A., Kushelevsky, A.P., and Schewach-Millet, M., 1990, The recovery from UVR-induced erythema and melanoma risk factors — A case study. J. Am. Acad. Dermatology, in press.
Beral, V., Evans, S., Shaw, H., and Milton, G., 1983, Cutaneous factors related to the risk of malignant melanoma. British Journal of Dermatology, 109:165–172.
Breathnach, A., and Wyllie, L., 1964, Electron microscopy of melanocytes and melanosomes in freckled human epidermis. Journal of Investigative Dermatology, 42:389–394.
Chedekel, M.R., 1982, Photochemistry and photobiology of epidermal melanins. Yearly Review. Photochemistry Photobiology, 35:881–885.
Elwood, J.M., Gallagher, R.P., Hill, G.B., Spinelli, J.J., Pearson, J.C.G., and Thralfall, W., 1984, Pigmentation and skin reaction to sun as risk factors for cutaneous melanoma: Western Canada Melanoma Study. British Medical Journal, 288:99–102.
Elwood, J.M., Williamson, D., and Stapleton, P.J., 1986, Malignant melanoma in relation to moles, pigmentation and exposure to fluorescent and other lighting sources. British Journal of Cancer, 53:65–74.
Harsanyi, Z.P., Post, P.W., Brinkmann, J.P., Chedekel, M.R., and Deibel, R.M., 1980, Mutagenicity of melanin from human red hair. Experientia 36:291–292.
Jung, E.G., Gunthart, K., Metzger, R.F.G., and Bohnert, E., 1981, Risk factors of the cutaneous melanoma phenotype. Archives of Dermatological Research, 270:33–36.
Kopf, A.W., Kripke, M.L., and Stern, R.S., 1984, Sun and malignant melanoma. Journal of the American Academy of Dermatology, 11:674–684.
Mantel, N., and Haenszel, W., 1959, Statistical aspects of the analysis of data from retrospective studies of disease. Journal of the National Cancer Institute, 22:719–748.
Oberley, L.W., and Buettner, G.R., 1979, Role of superoxide dismutase in cancer: A review. Cancer Research, 39:1141–1149.
Rhodes, A.R., Weinstock, M.A., Fitzpatrick, T.B., Mihm, M.C., and Sober, A.J., 1987, Risk factors for cutaneous melanoma. Journal of the American Medical Association,258:3146–3154.
Tannenbaum, L., Parrish, J.A., Haynes, H.A., Fitzpatrick, T.B., and Pathak, M.A., 1976, Prolonged ultraviolet light induced erythema and the cutaneous carcinoma phenotype. Journal of Investigative Dermatology, 67:513–517.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media New York
About this chapter
Cite this chapter
Azizi, E., Wax, Y., Lusky, A., Kushelevsky, A., Schewach-Millet, M. (1991). Prolonged UVR-Induced Erythema and Melanoma Risk Factors. In: Riklis, E. (eds) Photobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3732-8_77
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3732-8_77
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6661-4
Online ISBN: 978-1-4615-3732-8
eBook Packages: Springer Book Archive