Abstract
The DNA polymerase alpha of Halobacterium halobium is constituted of two pairs of Mr 70,000 and 60,000 subunits [1]. We have previously isolated a 70 kD protein immunologically related to v-myc oncogene product [2]. This v-myc like protein, purified with a totally different method from that used for the polymerase alpha, is identical with the Mr 70,000 subunit of the polymerase. In order to study the degree of homology of this polymerase with eucaryotic DNA polymerase alpha or with v-myc protein, we have started the cloning of the corresponding gene using the yeast DNA polI gene as probe.
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© 1991 Springer Science+Business Media New York
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Sorokine, I., Ben-Mahrez, K., Nakayama, M., Kohiyama, M. (1991). Enzymology and Genetics of an Alpha-Like DNA Polymerase from Halobacterium Halobium . In: Rodriguez-Valera, F. (eds) General and Applied Aspects of Halophilic Microorganisms. NATO ASI Series, vol 201. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3730-4_38
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DOI: https://doi.org/10.1007/978-1-4615-3730-4_38
Publisher Name: Springer, Boston, MA
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