Abstract
We have discovered the presence of dihydrolipoamide dehydrogenase (DHLipDH) in the halophilic archaeobacteria, despite the fact that these organisms lack the multienzyme complexes with which this enzyme is associated in eubacteria and eucaryotes. We will discuss (a) the discovery, purification and characterisation of the halophilic DHLipDH, (b) the detection of the substrate (reduced lipoic acid) in halophilic archaeobacteria, (c) the discovery of DHLipDH and lipoic acid in several other archaeobacterial genera, and (d) the function of DHLipDH in the archaeobacteria and its evolution with respect to the multienzyme complexes of eubacteria and eucaryotes.
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Danson, M.J., Hough, D.W., Vettakkorumakankav, N., Stevenson, K.J. (1991). Lipoic Acid and Dihydrolipoamide Dehydrogenase in Halophilic Archaeobacteria. In: Rodriguez-Valera, F. (eds) General and Applied Aspects of Halophilic Microorganisms. NATO ASI Series, vol 201. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3730-4_15
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DOI: https://doi.org/10.1007/978-1-4615-3730-4_15
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