Abstract
Various authors have observed and reported an association between perioperative blood transfusions and disease-free survival time in patients with malignant tumors. Interest in this relationship began from the observation that perioperative transfusions improved graft survival in patients undergoing kidney transplantation [1]. Based on these clinical data, in 1981 Gantt stated his belief that blood transfusions in patients with malignant tumors would give the tumor “a better chance to survive” [2]. Since that time clinical investigations have been carried out to confirm the relationship between perioperative blood transfusions and a worse prognosis. Most of the data concern colerectal cancer [3–7], lung cancer [8,9], breast cancer [7,10–12], soft tissue sarcomas [13], and head and neck cancer [14].
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References
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Chesi, R., Borghi, B., Lari, S. (1993). Perioperative blood transfusions and survival in osteosarcoma. In: Humphrey, G.B., Koops, H.S., Molenaar, W.M., Postma, A. (eds) Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies. Cancer Treatment and Research, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3518-8_4
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DOI: https://doi.org/10.1007/978-1-4615-3518-8_4
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