Abstract
In the last decade there have been dramatic improvements in chemotherapeutic protocols for osteosarcoma and, as such, there has been a tremendous increase in the disease-free survival period [1,10,13]. Therefore many more children will survive to adulthood after successful treatment of their tumors. Limb-sparing surgery has become an acceptable alternative to amputation in adults with primary bone tumors [5]. Reconstruction of a large segmental defect with the loss of one or more growth plates in a growing child continues to pose a difficult challenge. Recent advances in the field of orthopedic bioengineering have led to the development of prostheses that are durable enough for children and can be periodically expanded to compensate for limb length discrepancy [11,16–18].
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Kenan, S., DeSimone, D.P., Lewis, M.M. (1993). Limb sparing for skeletally immature patients with osteosarcoma: The expandable prosthesis. In: Humphrey, G.B., Koops, H.S., Molenaar, W.M., Postma, A. (eds) Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies. Cancer Treatment and Research, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3518-8_23
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DOI: https://doi.org/10.1007/978-1-4615-3518-8_23
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