Abstract
Histologic subclassification of osteosarcoma, with the exception of parosteal osteosarcoma [1–3], has not been regarded to be useful as a prognostic parameter. Nevertheless, it is now applied in routine surgical pathology. A generally accepted subclassification is the one by Dahlin and Unni of the Mayo Clinic [4,5] (Table16-1). Our experience is shown in Table 16-2. MFH-mimicking osteosarcoma, giant-cell-rich osteosarcoma, and dedifferentiation of intraosseous well-differentiated osteosarcoma are added.
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Ushigome, S., Nakamori, K., Nikaido, T., Takagi, M. (1993). Histologic subclassification of osteosarcoma: Differential diagnostic problems and immunohistochemical aspects. In: Humphrey, G.B., Koops, H.S., Molenaar, W.M., Postma, A. (eds) Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies. Cancer Treatment and Research, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3518-8_16
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