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A Population-based Trial of β-Carotene Chemoprevention of Head and Neck Cancer

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The Biology and Prevention of Aerodigestive Tract Cancers

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 320))

Abstract

Squamous cell carcinoma (SCC) of the upper aerodigestive tract (oral cavity, pharynx, and larynx) is a major health problem in the United States and throughout the world. It is estimated that 43,300 new cases will be identified and that 11,800 patients will die of these cancers in the United States in 1991 (1). In addition to the number of patients affected, cancers of the oral cavity, pharynx, and larynx assume a higher relative importance because of the functional impairment and cosmetic deformity associated with the cancer and its treatment.

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Author information

Authors and Affiliations

  1. Cancer Prevention Research Unit for Connecticut at Yale, Yale University School of Medicine, New Haven, Connecticut, USA

    Susan Taylor Mayne, Tongzhang Zheng & Dwight T. Janerich

  2. Department of Otolaryngology, University of Miami School of Medicine, Miami, Florida, USA

    W. Jarrard Goodwin Jr.

  3. Section of Hematology/Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut, USA

    Barbara G. Fallon

  4. Department of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut, USA

    Dennis L. Cooper

  5. Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA

    Craig D. Friedman

Authors
  1. Susan Taylor Mayne
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  2. Tongzhang Zheng
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  3. Dwight T. Janerich
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  4. W. Jarrard Goodwin Jr.
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  5. Barbara G. Fallon
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  6. Dennis L. Cooper
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  7. Craig D. Friedman
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Editor information

Editors and Affiliations

  1. The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA

    Guy R. Newell  & Waun Ki Hong  & 

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© 1992 Springer Science+Business Media New York

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Mayne, S.T. et al. (1992). A Population-based Trial of β-Carotene Chemoprevention of Head and Neck Cancer. In: Newell, G.R., Hong, W.K. (eds) The Biology and Prevention of Aerodigestive Tract Cancers. Advances in Experimental Medicine and Biology, vol 320. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3468-6_16

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  • DOI: https://doi.org/10.1007/978-1-4615-3468-6_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6536-5

  • Online ISBN: 978-1-4615-3468-6

  • eBook Packages: Springer Book Archive

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