Abstract
Neurotransmission is influenced by various astrocytic functions. One of the more important astrocytic functions is control of the ion composition in extracellular fluid. Changes in astrocytic volume are responsible for the maintenance of extracellular K+ and H+ concentrations in the CNS (Dietzel et al., 1982; Walz and Hinks, 1985). In fact, disturbance of astrocytic volume regulation is suggested to be involved in brain damage (Hertz, 1981). Taurine (Tau) is reported to be an osmoregulatory substance in the brain since Tau is released from astrocytes into the extracellular space by both high-K+ and hypotonic-induced volume increase (Pasantes-Morales and Schousboe, 1988; 1989; Martin et al., 1990). Numerous possible roles of the released Tau in neuronal pathological states have been suggested.
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© 1992 Springer Science+Business Media New York
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Koyama, Y., Ishibashi, T., Baba, A. (1992). L-Glutamate-Induced Swelling of Cultured Astrocytes. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_44
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DOI: https://doi.org/10.1007/978-1-4615-3436-5_44
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