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Review: Myocardial Physiological Effects of Taurine and Their Significance

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Taurine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 315))

Abstract

Recent interest in the role of taurine in the heart stems from the observation that cats fed a taurine deficient diet develop a cardiomyopathy1. This condition is reversible, as evidenced by the restoration of normal cardiac function upon dietary supplementation with taurine2. These studies have accelerated the search for a physiological function for taurine. Although several theories of taurine action have been proposed, none adequately accounts for all of the multiple properties and actions of taurine. Therefore, this review will address both the strengths and weaknesses of the present proposals, including the possibility that taurine may exhibit multiple physiological roles in the heart.

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Authors and Affiliations

  1. Department of Pharmacology, University of South Alabama School of Medicine, Mobile, AL, 36688, USA

    Stephen W. Schaffer

  2. Department of Medicine III, School of Medicine Osaka University, Osaka, Japan

    Junichi Azuma

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  1. Texas Tech University Health Sciences Center, Lubbock, Texas, USA

    John B. Lombardini

  2. University of South Alabama School of Medicine, Mobile, Alabama, USA

    Stephen W. Schaffer

  3. Osaka University Medical School, Osaka, Japan

    Junichi Azuma

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Schaffer, S.W., Azuma, J. (1992). Review: Myocardial Physiological Effects of Taurine and Their Significance. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_13

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