Abstract
By definition, active cerebral metabolic rate for oxygen (ACMRO2) is the oxygen consumption associated with the generation of spontaneous electrical activity.1 The balance, or basal CMRO2, is presumably, the oxygen consumed to maintain neuronal viability through ion pumping and reparative and synthetic metabolic pathways.2 This concept evolved out of interest in the mechanism of action of anesthetics and the hypothesis that the effect of anesthetics on cerebral metabolism is secondary to a direct effect on cerebral function.3
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References
J. D. Michenfelder, The interdependency of cerebral functional and metabolic effects following massive doses of thiopental in the dog, Anesthesiology 41: 231 (1974).
J. Astrup, P. M. Sorensen, H. R. Sorensen, Oxygen and glucose consumption related to Na+-K+ transport in canine brain, Stroke 12: 726 (1981).
S. S. Kety, Discussion. Pharmacol Rev 17: 230 (1965).
J. D. Michenfelder, R. A. Theye, In vivo toxic effects of halothane on canine cerebral metabolic pathways, Am. J. Physiol. 229:1050 (1975).
E. M. Nemoto, J. A. Melick, P. M. Winter, Active and basal cerebrometabolic rate for oxygen (CMRO2) after complete global brain ischemia in rats, in: Oxygen transport to tissue X.M. Mochizuki, C. R. Honig, T. Koyama, T. K. Goldstick, D.F. Bruley, eds., Plenum Publishing Corp., New York, 1988.
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© 1992 Springer Science+Business Media New York
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Nemoto, E.M., Yao, L., Yonas, H., Darby, J. (1992). Active and Basal Whole Brain Blood Flow, Oxygen and Glucose Metabolism in Monkeys. In: Erdmann, W., Bruley, D.F. (eds) Oxygen Transport to Tissue XIV. Advances in Experimental Medicine and Biology, vol 317. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3428-0_83
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DOI: https://doi.org/10.1007/978-1-4615-3428-0_83
Publisher Name: Springer, Boston, MA
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