Abstract
Liquid ventilation with oxygenated perfluorocarbons (PFC) has been shown to improve pulmonary gas exchange and lung mechanics in preterm animals with respiratory failure [1–4]. Histological studies also reveal that liquid ventilation is less harmful to the lung structures than conventional gas ventilation [3,5]. Moreover, the first human application of liquid ventilation has been reported with promising success in premature infants with severe respiratory distress in whom conventional therapies had failed [6].
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© 1992 Springer Science+Business Media New York
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Tütüncü, A.S., Lachmann, B., Faithfull, N.S., Erdmann, W. (1992). Dose Dependent Improvement of Gas Exchange by Intratracheal Perflubron (Perfluorooctylbromide) Instillation in Adult Animals with Acute Respiratory Failure. In: Erdmann, W., Bruley, D.F. (eds) Oxygen Transport to Tissue XIV. Advances in Experimental Medicine and Biology, vol 317. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3428-0_44
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DOI: https://doi.org/10.1007/978-1-4615-3428-0_44
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