Abstract
Positive end-expiratory pressure (PEEP) was suggested to be the therapy of the adult respiratory distress syndrome (ARDS) by Asbaugh and colleagues1. However recent articles clearly indicate that any type of ventilatory management is merely a supportive measure to provide adequate gas exchange and has little effect in treatment of the underlying pathology2–4. In spite of this knowledge, new mechanical ventilatory approaches have been continuously introduced in the last two decades, aiming to provide adequate oxygenation and to avoid damage to the lungs which could be caused by the ventilation mode itself (for review see B. Lachmann et al.5).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
D. G. Asbaugh, T. L. Petty, D. B. Bigelow, and T. M. Harris, Continuous positive-pressure breathing (CPPB) in adult respiratory distress syndrome, J Thorac Cardiovasc Surg. 57: 31–41 (1969).
J. A. Weigelt, Current concepts in the management of the adult respiratory distress syndrome, World J Surg. 11: 161–166 (1987).
D. J. Shale, The adult respiratory distress syndrome- 20 years on, Thorax. 42: 641–645 (1987).
R. W. Bolin, and D. J. Pierson, Ventilatory management of acute lung injury, Crit Care Clin. 2: 585–599 (1986).
B. Lachmann, E. Danzmann, B. Haendly, and B. Jonson, Ventilator settings and gas exchange in respiratory distress syndrome, in: O. Prakash (ed). Applied physiology in clinical respiratory care. Martinus Nijhoff Publishers, The Hauge (1982).
L. J. Greenfield, P. A. Ebert, and D. W. Benson, Effect of positive pressure ventilation on surface tension properties of lung extracts, Anesthesiology. 25: 312–316 (1964).
E. O. R. Reynolds, and A. Taghizadeh, Improved prognosis of infants mechanically ventilated for hyaline membrane disease, Arch Dis Child. 49: 505–515 (1974).
B. Lachmann, B. Jonson, M. Lindroth, and B. Robertson, Modes of artificial ventilation in severe respiratory distress syndrome. Lung function and morphology in rabbits after washout of alveolar surfactant, Crit Care Med. 10: 724–732 (1984).
K. G. Hickling, S. J. Henderson, and R. Jackson, Low mortality associated with pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome, Intensive Care Med. 16: 372–377 (1990).
P. C. Lee, C. M. Helsmoortel, S. M. Cohn, and M. P. Fink, Are low tidal volumes safe? Chest. 97: 425–429 (1990).
B. Lachmann, B. Haendly, H. Schultz, and B. Jonson, Improved oxygenation, CO2 elimination, compliance and decreased barotrauma following changes of volume-generated PEEP ventilation with inspiratory/expiratory (I/E) ratio of 1:2 to pressure-generated ventilation with I/E ratio of 4:1 in patients with severe adult respiratory distress syndrome (ARDS), Intensive Care Med. 6: 64 (1980).
S. J. Boros, S. V. Matalon, R. Ewald, A. S. Leonard, and C. E. Hunt, The effect of independent variations in inspiratory-expiratory ratio and end-expiratory pressure during mechanical ventilation in hyaline membrane disease: the significance of mean airway pressure, J Pediatr. 91: 794–798 (1977).
A. G. Cole, S. F. Weiler, and M. K. Sykes, Inverse ratio ventilation compared with PEEP in adult respiratory failure, Intensive Care Med. 10: 227–232 (1984).
L. Gattinoni, A. Pesenti, M. L. Caspani, A. Pelizzola, D. Mascheroni, R. Marcolin, G. Iapichino, M. Langer, A. Agostoni, T. Kolobow, and G. Damia, Low frequency positive-pressure ventilation with extracorporeal CO2 removal in severe acute respiratory failure, JAMA. 256: 881–886 (1986).
R. R. Kirby, J. B. Downs, J. M. Civetta, J. H. Modell, F. J. Dannemiller, E. F. Klein et al, High level positive end-expiratory pressure (PEEP) in acute respiratory insufficiency, Chest. 67: 156–163 (1975).
R. S. Tharratt, R. B. Allen, and T. E. Albertson, Pressure controlled inverse ratio ventilation in severe adult respiratory failure, Chest. 94: 755–762 (1988).
K. G. Hickling, Ventilatory management of ARDS: can it affect the outcome? Intensive Care Med. 16: 219–226 (1990).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Kesecioglu, J. et al. (1992). Comparison of Different Modes of Artificial Ventilation with Extracorporeal CO2 Elimination on Gas Exchange in an Animal Model of Acute Respiratory Failure. In: Erdmann, W., Bruley, D.F. (eds) Oxygen Transport to Tissue XIV. Advances in Experimental Medicine and Biology, vol 317. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3428-0_110
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3428-0_110
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6516-7
Online ISBN: 978-1-4615-3428-0
eBook Packages: Springer Book Archive