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Safety and Efficacy in Boron Neutron Capture Therapy

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Abstract

Boron neutron capture therapy (BNCT) is an attractive mode of radiotherapy. Its great potential lies in the fact that physiological differences between healthy and tumor cells can be utilized to enhance the dose to tumor cells selectively. This is achieved by administering, prior to the radiation treatment, a boron compound that can selectively accumulate or be retained in the desired target cells. Subsequently, the organ containing the tumor is irradiated with neutrons. Boron-10, by virtue of its high neutron capture cross section, will give rise to two densely ionizing particles through the 10B(n,α)7Li neutron capture reaction.

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© 1992 Springer Science+Business Media New York

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Gabel, D. (1992). Safety and Efficacy in Boron Neutron Capture Therapy. In: Gabel, D., Moss, R. (eds) Boron Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3408-2_3

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  • DOI: https://doi.org/10.1007/978-1-4615-3408-2_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6506-8

  • Online ISBN: 978-1-4615-3408-2

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