Abstract
The Australian research program in Neutron Capture Therapy (NCT) had its beginnings in 19821,2 following a visit by the author to Professor Hatanaka in Japan. While the commitment by Ansto has been restrained and relatively constant in recent years at 2-3 person years pa, that of university and medical collaborators continues to grow. This growth in Australian interest has been mirrored by that in the USA, Europe and Japan, and symposia and workshops are now common on the international scene.
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References
Allen, B.J. Boron neutron capture therapy-a research program for glioblastoma and melanoma. Aust. Phys. Eng. Sci. Med. 6, 184–186 (1983).
Allen, B.J. In vitro and in vivo studies in boron neutron capture therapy of malignant melanoma. Proc. First Int. Symp. Neutron Capture Therapy, MIT, Boston, Oct. 1983. Fairchild, R.G.; Brownell G.L., eds., BNL51730, 341–354.
Tamat, S.R.; Moore, D.E.; Patwardhan, A.; Hersey, P. Boronated monoclonal antibody 225.28S for potential use in neutron capture therapy of malignant melanoma. Pigm. Cell Res. 2, 278–280 (1989).
Wilson, J.G. Synthetic approach to a decarboranyl thiouracil. Pigm. Cell Res. 2, 297–303 (1989).
Wilson, J.G. Carborane compounds for neutron capture therapy ofmalignant melanoma. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 227–230 (1992).
Moore, D.E.; Chandler, A.K.; Corderoy-Buck, S.; Wilson, G.J.; Allen, B.J. Liposomes as carriers of boronated thiouracils for N CT of melanomas. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 451–454 (1992).
Martin, R.F.; Haigh, A.; Monger., C.; Pardee, M.; Whittaker, A.; Kelly, D.P.; Allen, B.J. 157Gd neutron capture: Potential of 157Gd-labelled DNA ligands for neutron capture therapy. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 357–360 (1992).
Brown, J.K.; Mountford, M.H.; Allen, B.J.; Mishima, Y.; Thihashi, M.; Parsons, P. Neutron irradiation of human melanoma cells. Pigm. Cell Res. 2, 319–324 (1989).
Brown, J.K.; Allen, B.J.; Chapman, J.E.; Mountford, M.H.; Parsons, P. In vitro incorporation of BPA by amelanotic and melanotic murine malignant melanoma cells. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 369–372 (1992).
Ichihashi, M.; Fukuda, H.; Brown, J.K.; Mountford, M.H.; Allen, B.J.; Mishima, Y. In vitro evaluation of BPA for melanoma at Moata in joint work between Japan and Australia BNCT research teams. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 387–390 (1992).
Allen, B.J.; Corderoy-Buck, S.; Moore, D.E.; Mishima, Y.; Ichihashi, M. Local control of murine melanoma xenografts in nude mice by neutron capture therapy. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 425–428 (1992).
Corderoy-Buck, S.; Allen, B.J.; Wilson, J.G.; Brown, J.K.; Mountford, M.; Tjarks, W.; Gabel, D.; Barkla, D.; Chandler, A.; Moore, D.E.; Patwardhan, A. Investigation of boron conjugated thiouracil derivatives for neutron capture therapy of melanoma. In: Advances in Radiopharmacology. Maddalena, D.J., ed., 114–127 (1990).
Tamat, S.R.; Patwardhan, A.; Moore, D.E.; Kabral, A.; Bradstock, K.; Hersey, P.; Allen, B.J. Boronated monoclonal antibodies for potential neutron capture therapy of malignant melanoma and leukaemia. Strahlenther. Onkol. 165, 145–147 (1989).
Mallesch, J.L.; Chiaraviglio, D.; Allen, B.J.; Moore, D.E. An intrapancreatic and hepatic model for Boron Neutron Capture Therapy. AINSE Radiobiology Conference, Sydney, October, 1991. Abstract.
Hill, J.S.; Kahl, S.B.; Kaye, A.H.; Gonzales, M.F.; Vardaxis, N.; Johnson, C.I.; Stylli, S.S.; Nakamura, Y. Tumour localisation of boronated porphyrin in an intracerebral model of glioma. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 501–506 (1992).
Tamat, S.R.; Moore, D.E.; Allen, B.J. Boron assay in biological tissue by inductively coupled plasma atomic emission spectroscopy. Anal. Chem. 59, 2161–2164 (1987).
Moore, D.E.; Dawes, A.L.; Allen, B.J.; Bradstock, K.F. Tracking of boron labelled monoclonal antibodies by energy loss spectroscopy in the electron microscopes. In: Advances in Radiopharmacology. Maddalena, D.J., ed., 114–127 (1990).
Moore, D.E.; Stretch, J.R.; Dawes, A.C.; Cockayne, D.; Allen, B.J.; Constantine, G. Uptake ofboronated monoclonal antibodies by melanoma cells visualised by track etch autoradiography and electron energy loss spectroscopy. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 335–338 (1992).
Barkla, D.H.; Allen, B.J.; Brown, J.K.; Mountford, M.H.; Ichihashi, M.; Mishima, Y. Morphological changes in human melanoma cells following irradiation with thermal neutrons. Pigm. Cell Res. 2, 345–348 (1989).
Barkla, D.H.; Brown, J.K.; Meriaty, H.; Allen, B.J. Ultrastructural changes in tumour cells following high or low LET radiation. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 395–398 (1992).
Elliston, P.; Pope, J.; Allen, B.J. In vivo determination of boron concentrations in rat tumours using boron-11 nuclear magnetic resonance spectroscopy. EPSM91, Sydney, July 1991. Abstract.
Narayan, K.; Spiropoulos, A. The radio responsiveness of normal and tumour microvasculature. Australas. Radiol. 34, 312–316 (1990).
Allen, B.J.; Brown, J.K; Harrington, B.; Izard, B.; Linklater, H.; Maddalena, D.J.; McNeill, J.; McGregor, B.J.; Mountford, M.H.; Snowdon, G.M.; Wilson, D.J.; Wilson, J.G.; Parsons, P.; Moore, D.; Tamat, S.; Hersey, P. Neutron capture therapy research for malignant melanoma. In: Neutron Capture Therapy. Hatanaka, H., ed., Nishimura, Niigata, 258–280 (1986).
Crotty, K.; Mallesch, J.; Moore, D.E.; Allen, B.J. Histological examination of melanoma xenografts in the nude mouse model; pre and post neutron capture therapy. AINSE Radiobiology Conference, Sydney, October 1991. Abstract.
Martin, R.J.; D'Cunha, G.; Pardee, M.; Allen, B.J. Induction of double strand breaks following neutron capture therapy in DNA bound 157Gd. Int. J. Radiat. Biol. 54, 205–208 (1988).
Martin, R.F.; D'Cunha, G.; Pardee, M.; Allen, B.J. Introduction of DNA double strand breaks by 157Gd neutron capture. Pigm. Cell Res. 2, 330–332 (1989).
Allen, B.J.; McGregor, B.J.; Martin, R.F. Neutron capture therapy with gadolinium-157. Strahlenther. Onkol. 165, 156–157 (1989).
McGregor, B.J.; Allen, B.J. Filtered beam dose distributions for boron neutron capture therapy of brain tumours. Aust. Phys. Eng. Sci. Med. 7, 27–34 (1984).
Harrington, B.V. Optimisation of an epithermal beam in HIF AR for boron neutron capture therapy. Ansto/E662 (1987).
Harrington, B.V. A calculational study of tangential and radial beams in HIFAR. In: Neutron Beam, Design, Development and Performance for Neutron Capture Therapy. Harling, O.K.; Bernard, J.A.; Zamenhof, R.G., eds., Plenum Press, New York, 97–106 (1990).
Storr, G.J.; Allen, B.J.; Harrington, B.V.; Davis, L.R; Elcombe, M.M.; Meriaty, H. Design considerations for the proposed HIF AR thermal and epithermal NCT facility. In: Progress in Neutron Capture Therapy for Cancer. Allen, B.J.; Moore, D.E.; Harrington, B.V., eds., Plenum Press, New York, 79–82 (1992).
Storr, G. Ideal neutron beam assessment for NCT, submitted.
Allen, B.J. Third generation neutron capture therapy for glioblastoma and melanoma brain metastases. Cancer Forum 14, 35–36 (1990).
Allen, B.J. Epithermal neutron capture therapy: a new modality for the treatment of glioblastoma and melanoma metastatic to the brain. Med. J. Aust. 153, 296–298 (1990).
Allen, B.J. Potential of neutron capture therapy for the treatment of localised terminal cancer. Australas. Radiol. 34, 297–305 (1990).
Blagojevic, N.; Allen, B.J.; Storr, G.; Hatanaka, H.; Nakagawa, H. The role of heavy water in dose-depth enhancement in Thermal Neutron Capture Therapy. AINSE Radiobiology Conference, Sydney, October 1991. Abstract.
Allen, B.J.; Coates, A.S.; McCarthy, W.H.; Mameghan, H.; Mishima, Y.; Ichihashi, M. Thermal neutron capture therapy: The JapanaseAustralian clinical trial for malignant melanoma. In: Clinical Aspects of Neutron Capture Therapy, Brookhaven National Laboratory. Fairchild, R.G.; Bond, V.P.; Woodhead, A.D., eds., Plenum Press, New York, 69–73 (1989).
Constantine, G. Epithermal Neutron Capture Therapy Facility for HIFAR, February 1991; unpublished report.
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Allen, B.J. (1992). The Implementation Strategy for BNCT Trials in Australia. In: Gabel, D., Moss, R. (eds) Boron Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3408-2_26
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DOI: https://doi.org/10.1007/978-1-4615-3408-2_26
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