Abstract
The goal of radiotherapy is the deposition of a high dose in the target volume to inactivate every single cell of a tumor without irradiating the normal tissues to a level giving rise to complications. The negative pions as charged particles have favorable properties concerning physical dose distribution. In addition, at the end of the range they undergo a nuclear reaction with target nuclei, liberating neutral and charged secondary particles, some of them with an increased radiobiological efficiency. For these reasons they were considered particularly suited for radiotherapy. To make optimum use of the particles, a new delivery technique was developed to fit the dose distributions in three dimensions to the target volume. With the developed therapy modality it was expected, after a stepwise optimization of the treatment, to reach an increased local control rate with equal or lower complication probability.
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© 1992 Springer Science+Business Media New York
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Blattmann, H. (1992). Treatment Planning and Optimization for Pion Therapy. In: Gabel, D., Moss, R. (eds) Boron Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3408-2_15
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DOI: https://doi.org/10.1007/978-1-4615-3408-2_15
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