Abstract
As early as 1911, Winterstein postulated his famous “reaction theory” reducing the hypoxic and hypercapnic ventilatory drives to one and the same mechanism at chemoreceptors, namely protons dissociated either from carbonic acid or from fixed acids generated during oxygen deficiency. However, after the discovery of the O2-sensitive arterial chemoreceptors, this fascinating idea had to be restricted to the central chemosensitivity, e.g. to the alternative whether H+ or molecular CO2 is the adequate stimulus.
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© 1992 Springer Science+Business Media New York
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Kiwull-Schöne, H., Kiwull, P. (1992). Hypoxia and the “Reaction Theory” of Central Respiratory Chemosensitivity. In: Goldstick, T.K., McCabe, M., Maguire, D.J. (eds) Oxygen Transport to Tissue XIII. Advances in Experimental Medicine and Biology, vol 316. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3404-4_40
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DOI: https://doi.org/10.1007/978-1-4615-3404-4_40
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