Abstract
Oxygenation-deoxygenation state of Hb in living tissues has been measured by means of near-infrared (NIR) spectrophotometry. Several authors have examined quantitative analysis of Hb oxygenation in brain, skeletal muscle, and other organs by using 2- or 3-wavelength NIR spectrophotometry (Hazeki and Tamura, 1988; Wray et al., 1988) and multicomponent analysis of NIR spectra (Araki and Nashimoto, 1989). Measurement of spatial distribution of this parameter by NIR spectrophotometry, however, has not been established yet. We have measured 2-wavelength NIR projection images of the human forearm and obtained an image showing 2-dimensional distribution of Hb oxygenation state in vivo.
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References
Hazeki, O., and Tamura, M., 1988, Quantitative analysis of hemoglobin oxygenation state of rat brain in situ by near-infrared spectrophotometry, J. Appl. Physiol., 64:796–802.
Wray, S., Cope, M., Delpy, D.T., Wyatt, J.S., and Reynolds, E.O.R., 1988, Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation, Biochim. Biophys. Acta, 933:184–192.
Araki, R., and Nashimoto, I., 1989, Multicomponent analysis of near-infrared spectra of anesthetized rat head: (II) Quantitative mUltivariate analysis of hemoglobin and cytochrome oxidase by non-negative least squares method, Adv. Exp. Med. Biol., 248:11–20.
Hampson, N.B., and Piantadosi, C.A., 1988, Near infrared monitor human skeletal muscle oxygenation during forearm ischemia, J. Apr ol., 64:2449–2457.
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© 1992 Springer Science+Business Media New York
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Araki, R., Nashimoto, I. (1992). Near-Infrared Imaging in vivo (II): 2-Dimensional Visualization of Tissue Oxygenation State. In: Goldstick, T.K., McCabe, M., Maguire, D.J. (eds) Oxygen Transport to Tissue XIII. Advances in Experimental Medicine and Biology, vol 316. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3404-4_20
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DOI: https://doi.org/10.1007/978-1-4615-3404-4_20
Publisher Name: Springer, Boston, MA
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