T Cell Adhesion Cascades: General Considerations and Illustration with CD31

  • Yoshiya Tanaka
  • Stephen Shaw
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 323)


Widespread appreciation of the importance of T cell adhesion has emerged only in the last 5-10 years. But now the topic is being widely discussed and many aspects carefully reviewed.1-8 This review briefly outlines one important emerging concept, namely that adhesion is not a simple unitary event but rather a co-ordinated sequence of events. This concept is emerging concurrently from studies in a variety of model systems.3,9-12 We illustrate how this concept has emerged from ours and others studies of T cells. Many aspects of T cell adhesion and biology are touched on which are beyond the scope of this brief presentation; the citations therefore emphasize reviews as a starting point for further reading.


Cell Binding Integrin Function Leukocyte Adhesion Deficiency Naive Cell Integrin Molecule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Yoshiya Tanaka
    • 1
  • Stephen Shaw
    • 1
  1. 1.Experimental Immunology BranchNational Cancer Institute National Institutes of HealthBethesdaUSA

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