Regulatory Cells and Cytokines Involved in Primary B Lymphocyte Production

  • Kenneth Dorshkind
  • Ramaswamy Narayanan
  • Kenneth S. Landreth
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 323)


Considerable progress has recently been made in defining cells and molecules that regulate the production of B lymphocytes in the bone marrow. Acquisition of this information is a direct result of advances in molecular biology and the development of cellular systems that permit the process of primary B cell differentiation to be duplicated in culture. As a result, it is possible now to present a working model of B cell development which identifies distinct proliferative and differentiative factors and the developmental stages on which they act.


Stromal Cell Bone Marrow Stromal Cell Stromal Cell Line Light Chain Gene Light Chain Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Kenneth Dorshkind
    • 1
    • 2
    • 3
  • Ramaswamy Narayanan
    • 1
    • 2
    • 3
  • Kenneth S. Landreth
    • 1
    • 2
    • 3
  1. 1.Division of Biomedical SciencesUniversity of CaliforniaRiversideUSA
  2. 2.Department of Molecular GeneticsHoffmann-LaRoche, Inc.NutleyUSA
  3. 3.The Department of Microbiology and Immunology and Mary Babb Randolph Cancer CenterWest Virginia UniversityMorgantownUSA

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