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Dose Modification by Neutron Capture in Cell Culture Using a 1 MeV Mean Energy Fission Neutron Beam

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Progress in Neutron Capture Therapy for Cancer

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Abstract

Experiments in a d(14)+Be fast neutron beam at the Essen Cyclotron demonstrate an enhancement of dose by neutron capture reactions which could be useful for clinical application (1,2). Based on these results, we underwent similar experiments using a different beam configuration. At the Low Flux Reactor in Petten, fast fission neutrons from a 235U-converter with a mean energy of 1.0 MeV are available to irradiate animals or cells using the Biological Irradiation Facility BIBOP (3,4,5). This facility has been used to obtain more information about dose modification by neutron capture reactions in non (epi-)thermal neutron beams.

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Literature

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Author information

Authors and Affiliations

  1. Dept. of Radiotherapy, University Hospital, Essen, Germany

    Wolfgang Sauerwein, Heike Szypniewski & Fred Pöller

  2. Radiobiology & Radioecology, Netherlands Energy Research Foundation ECN, Petten, The Netherlands

    René Huiskamp

Authors
  1. Wolfgang Sauerwein
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  2. Heike Szypniewski
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  3. Fred Pöller
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  4. René Huiskamp
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Editor information

Editors and Affiliations

  1. Australian Nuclear Science and Technology Organisation, Menai, New South Wales, Australia

    Barry J. Allen  & Baiba V. Harrington  & 

  2. University of Sydney, Sydney, New South Wales, Australia

    Douglas E. Moore

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© 1992 Springer Science+Business Media New York

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Sauerwein, W., Szypniewski, H., Pöller, F., Huiskamp, R. (1992). Dose Modification by Neutron Capture in Cell Culture Using a 1 MeV Mean Energy Fission Neutron Beam. In: Allen, B.J., Moore, D.E., Harrington, B.V. (eds) Progress in Neutron Capture Therapy for Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3384-9_88

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  • DOI: https://doi.org/10.1007/978-1-4615-3384-9_88

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6494-8

  • Online ISBN: 978-1-4615-3384-9

  • eBook Packages: Springer Book Archive

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