Abstract
Neutron capture therapy (NCT) applied by means of an external neutron beam has been extensively studied in the last 3 decades. Another option for the neutron capture (NC) reaction, the enhancement of tumor dose by interstitial Californium-252 implant, has been proposed recently9. Most sigmoid dose response curves for neutron irradiation are very steep and therefore even a small (few %) enhancement of tumor dose may dramatically change the clinical outcome. The potential of boron-10 as a capture agent is very well known but new methods of selective delivery of other isotopes into tumor cells may make them useful in NCT.
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© 1992 Springer Science+Business Media New York
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Wierzbicki, J., Maruyama, Y., Martin, R. (1992). Enhancement of Tumor Dose by the Gadolinium Neutron Capture Reaction in Cf-252 Brachytherapy. In: Allen, B.J., Moore, D.E., Harrington, B.V. (eds) Progress in Neutron Capture Therapy for Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3384-9_36
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DOI: https://doi.org/10.1007/978-1-4615-3384-9_36
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