Skip to main content
SpringerLink
Log in
Book cover

Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle pp 137–148Cite as

Effects of Calcium Release from the Sarcoplasmic Reticulum on Intramembrane Charge Movement in Skeletal Muscle

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 311))

Abstract

Skeletal muscle contraction is initiated by the increase in the intracellular calcium concentration ([Ca2+]) following the depolarization of the surface- and transverse-(T-) tubular membranes (see the review by Ebashi, 1991). Calcium ions are released into the myoplasm from an intracellular store, the sarcoplasmic reticulum (SR), through the ryanodine receptor calcium release channel (Imagawa et al., 1987; Inui et al., 1987). The voltage sensitive step that links channel opening to depolarization is the displacement of permanent charges (charge movement, Schneider and Chandler, 1973) found in the T-tubular membrane and localized in the DHP receptor (Ríos and Pizarro, 1991).

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Adrian, R. H. and Peres, A., 1977, A ‘gating’ signal for the potassium channel? Nature (Lond.), 267:800.

    Article  CAS  Google Scholar 

  • Almers, W., Adrian, R. H. and Levinson, S. R., 1975, Some dielectric properties of muscle membrane and their possible importance for excitation-contraction coupling, Ann. NY Acad. Sci., 264:278.

    Article  PubMed  CAS  Google Scholar 

  • Brum, G., and Ríos, E., 1987, Intramembrane charge movement in frog skeletal muscle fibres. Properties of charge-2, J. Physiol. (Lond.), 387:489.

    CAS  Google Scholar 

  • Brum, G., Ríos, E., and Schneider, M. F., 1988a, A quantitative model of calcium removal from the myoplasmic solution (Appendix to Brum, G., Ríos, E., and Stefani, E. (1988) Effects of extracellular calcium on calcium movements of excitation-contraction coupling in frog skeletal muscle fibers), J. Physiol. (Lond.), 398:441.

    CAS  Google Scholar 

  • Brum, G., Ríos, E., and Stefani, E., 1988b, Effects of extracellular calcium on calcium movements of excitation-contraction coupling in frog skeletal muscle fibers, J. Physiol. (Lond.), 398:441.

    CAS  Google Scholar 

  • Csernoch, L., Huang, C. L.-H., Szücs, G., and Kovács, L., 1988, Differential effects of tetracaine on charge movements and Ca2+ signals in frog skeletal muscle, J. Gen. Physiol., 92:601.

    Article  PubMed  CAS  Google Scholar 

  • Csernoch, L., Pizarro, G., Uribe, I., Rodríguez, M., and Ríos, E., 1991, Interfering with calcium release suppresses Iγ, the “hump” component of intramembranous charge movement in skeletal muscle, J. Gen. Physiol., 97:845.

    Article  PubMed  CAS  Google Scholar 

  • Duane, S. and Huang, C. L.-H., 1982, A quantitative description of the voltage dependent capacitance in frog skeletal muscle in terms of equilibrium statistical mechanics. Proc. R. Soc. Lond. B Biol., 215:75.

    Article  CAS  Google Scholar 

  • Ebashi, S., 1991, Excitation-contraction coupling and the mechanism of muscle contraction, Ann. Rev. Physiol., 53:1.

    Article  CAS  Google Scholar 

  • García, J., Amador, E., and Stefani, E., 1989, Relationship between myoplasmic Ca transients and Ca current in frog skeletal muscle, J. Gen. Physiol., 94:973.

    Article  PubMed  Google Scholar 

  • Horowicz, P., and Schneider, M. F., 1981, Membrane charge moved at contraction thresholds in skeletal muscle fibres, J. Physiol. (Lond.), 314:595.

    CAS  Google Scholar 

  • Huang, C. L.-H., 1981, Effects of local anaesthetics on the relationship between charge movements and contractile thresholds in frog skeletal muscle, J. Physiol. (Lond.), 320:381.

    CAS  Google Scholar 

  • Huang, C. L.-H., 1983, Time domain spectroscopy of the membrane capacitance in frog skeletal muscle, J. Physiol. (Lond.), 341:1.

    CAS  Google Scholar 

  • Huang, C. L.-H., 1989, Intramembrane charge movements in skeletal muscle, Physiol. Rev., 68:1197.

    Google Scholar 

  • Hui, C. S., 1983a, Pharmacological studies of charge movement in frog skeletal muscle, J. Physiol. (Lond.), 337:509.

    CAS  Google Scholar 

  • Hui, C. S., 1983b, Differential properties of two charge components in frog skeletal muscle, J. Physiol. (Lond.), 337:531.

    CAS  Google Scholar 

  • Imagawa, T., Smith, J. S., Coronado, R., and Campbell, K. P., 1987, Purified ryanodine receptor from skeletal muscle sarcoplasmic reticulum is the Ca2+ permeable pore of the calcium release channel, J. Biol., Chem., 262:16636.

    CAS  Google Scholar 

  • Inui, M., Saito, A., and Fleischer, S., 1987, Purification of the ryanodine receptor and identity with feet structures of junctional terminal cisternae of sarcoplasmic reticulum from fast skeletal muscle, J. Biol. Chem., 262:1740.

    PubMed  CAS  Google Scholar 

  • Jacquemond, V., Csernoch, L., Klein, M. G., and Schneider, M. F., 1991, Voltage-gated and calcium-gated calcium release during depolarization of skeletal muscle fibers, Biophys. J., 60:in press.

    Google Scholar 

  • Kovács, L., Ríos, E., and Schneider, M. F., 1983, Measurement and modification of free calcium transients in frog skeletal muscle fibres by a metallochromic indicator dye, J. Physiol. (Lond.), 343:161.

    Google Scholar 

  • Kovács, L., and Schneider, M. F., 1978, Contractile activation by voltage clamp depolarization of cut skeletal muscle fibres, J. Physiol. (Lond.), 277:483.

    Google Scholar 

  • Kovács, L., and Szücs, G., 1983, Effect of caffeine on intramembrane charge movement and calcium transients in cut skeletal muscle fibres of the frog, J. Physiol. (Lond.), 341:559.

    Google Scholar 

  • Meissner, G., 1986, Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum, J. Biol. Chem., 261:6300.

    PubMed  CAS  Google Scholar 

  • Melzer, W., Ríos, E., and Schneider, M. F., 1987, A general procedure for determining calcium release from the sarcoplasmic reticulum in skeletal muscle fibers, Biophys. J., 51:849.

    Article  PubMed  CAS  Google Scholar 

  • Pizarro, G., Csernoch, L., Uribe, I., Rodríguez, M., and Ríos, E., 1991, The relationship between Qγ and Ca release from the sarcoplasmic reticulum in skeletal muscle, J. Gen. Physiol., 97:913.

    Article  PubMed  CAS  Google Scholar 

  • Pizarro, G., Rodriguez, M., Csernoch, L., and Ríos, E., 1990, Positive feedback in skeletal muscle E-C coupling, Biophys. J., 57:401a.

    Google Scholar 

  • Ríos, E., and Pizarro, G., 1988, Voltage sensors and calcium channels of excitation-contraction coupling. NIPS, 3:223.

    Google Scholar 

  • Ríos, E., and Pizarro, G., 1991, The voltage sensor of excitation-contraction coupling in skeletal muscle, Physiol. Rev., 71:849.

    PubMed  Google Scholar 

  • Schneider, M. F., and Chandler, W. K., 1973, Voltage dependent charge movement in skeletal muscle: a possible step in excitation-contraction coupling, Nature, 242:244.

    Article  PubMed  CAS  Google Scholar 

  • Schneider, M. F., and Simon, B. J., 1988, Inactivation of calcium release from the sarcoplasmic reticulum in frog skeletal muscle, J. Physiol. (Lond.), 405:727.

    CAS  Google Scholar 

  • Simon, B. J., Klein, M. G., and Schneider, M. F., 1991, Calcium dependence of inactivation of calcium release in frog skeletal muscle, J. Gen. Physiol., 97:437.

    Article  PubMed  CAS  Google Scholar 

  • Szücs, G., Csernoch, L., Magyar, J., and Kovács, L., 1991, Contraction threshold and the “hump” component of charge movement in frog skeletal muscle, J. Gen. Physiol., 97:897.

    Article  PubMed  Google Scholar 

  • Vergara, J., and Caputo, C., 1983, Effects of tetracaine on charge movements and calcium signals in frog skeletal muscle fibers, Proc. Natl. Acad. Sci. (USA), 80:1477.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dept. of Physiol., Univ. Med. Sch., Debrecen, Hungary

    László Csernoch & Géza Szücs

  2. Dept. of Physiol., Rush Univ., Chicago, IL, USA

    Gonzalo Pizarro & Eduardo Ríos

  3. Dept. of Physiol., Baylor Col. of Medicine, Houston, TX, USA

    Jesús García & Enrico Stefani

Authors
  1. László Csernoch
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gonzalo Pizarro
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jesús García
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Géza Szücs
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Enrico Stefani
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Eduardo Ríos
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Alberta, Edmonton, Alberta, Canada

    George B. Frank

  2. Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    C. Paul Bianchi

  3. University of Calgary, Calgary, Alberta, Canada

    Henk E. D. J. ter Keurs

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer Science+Business Media New York

About this chapter

Cite this chapter

Csernoch, L., Pizarro, G., García, J., Szücs, G., Stefani, E., Ríos, E. (1992). Effects of Calcium Release from the Sarcoplasmic Reticulum on Intramembrane Charge Movement in Skeletal Muscle. In: Frank, G.B., Bianchi, C.P., ter Keurs, H.E.D.J. (eds) Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle. Advances in Experimental Medicine and Biology, vol 311. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3362-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-3362-7_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6483-2

  • Online ISBN: 978-1-4615-3362-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation