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Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin pp 57–74Cite as

ELISA and Its Application for Residue Analysis of Antibiotics and Drugs in Products of Animal Origin

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Abstract

Development and application of enzyme-linked immunosorbent assays (ELISAs) for analysis of antibiotics and drugs used therapeutically and subtherapeutically in food producing animals have increased in the last decade. These immunochemical methods are capable of detecting low levels of residues in tissues as well as biological fluids (urine, blood, milk). These assays are rapid, sensitive, cost effective, require little sample clean-up and lend themselves to routine testing of large numbers of samples. They can be used for qualitative screening or quantitative analysis. The presentation will include a discussion of the principles of ELISAs. Examples of ELISAs for detection of specific drugs will be presented which include sulfonamides, chloramphenicol, B-lactams and aminoglycosides.

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Authors and Affiliations

  1. Neogen Corporation, 620 Lesher Place, Lansing, MI, 48912, USA

    Deborah E. Dixon-Holland

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  1. Deborah E. Dixon-Holland
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Editors and Affiliations

  1. The Connecticut Agricultural Experiment Station, New Haven, Connecticut, USA

    Vipin K. Agarwal

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© 1992 Springer Science+Business Media New York

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Dixon-Holland, D.E. (1992). ELISA and Its Application for Residue Analysis of Antibiotics and Drugs in Products of Animal Origin. In: Agarwal, V.K. (eds) Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3356-6_5

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  • DOI: https://doi.org/10.1007/978-1-4615-3356-6_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6480-1

  • Online ISBN: 978-1-4615-3356-6

  • eBook Packages: Springer Book Archive

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