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The Immunobiology of Human Macrophage Fcγ Receptors

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Combination Therapies

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Abstract

At least three biochemically distinct Fcγ receptor classes have been described on human cells. These receptors have been designated FcγRI, FcγRII and FcγRIII. They are membrane glycoproteins with extracellular domains that contain immunoglobulin-like regions. Therefore, they are members of the immunoglobulin gene superfamily. They appear to be located on human chromosome 1 and may have arisen from gene duplication. All three Fcγ receptors are present on the surface of human macrophages.

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Author information

Authors and Affiliations

  1. The University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Alan D. Schreiber, Arnold I. Levinson & Milton D. Rossman

Authors
  1. Alan D. Schreiber
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  2. Arnold I. Levinson
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  3. Milton D. Rossman
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Editors and Affiliations

  1. The George Washington University School of Medicine, Washington, D.C., USA

    Allan L. Goldstein

  2. University of Rome “Tor Vergata”, Rome, Italy

    Enrico Garaci

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© 1992 Springer Science+Business Media New York

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Schreiber, A.D., Levinson, A.I., Rossman, M.D. (1992). The Immunobiology of Human Macrophage Fcγ Receptors. In: Goldstein, A.L., Garaci, E. (eds) Combination Therapies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3340-5_25

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  • DOI: https://doi.org/10.1007/978-1-4615-3340-5_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6472-6

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