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Thymosin: An Innovative Approach to the Treatment of Chronic Hepatitis B

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Book cover Combination Therapies

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Abstract

Chronic hepatitis B virus infection is a common disease afflicting 300 million people worldwide, including approximately one million Americans who are carriers of the hepatitis B surface antigen (HBSAg). Many such carriers have concomitant chronic liver disease and are at risk for developing cirrhosis, liver failure and hepatocellular carcinoma (1, 2). Impaired effectiveness of the host cellular immune mechanisms in clearing hepatitis B virus (HBV) infected hepatocytes has been proposed to explain development of chronic HBV infection (3, 4).

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Author information

Authors and Affiliations

  1. Department of Medicine, Wayne State University School of Medicine, Detroit, MI, 48201, USA

    Milton G. Mutchnick & Glen D. Cummings

  2. Liver Disease Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA

    Jay H. Hoofnagle

  3. Liver Research Center, Albert Einstein College of Medicine, New York, NY, 10461, USA

    David A. Shafritz

Authors
  1. Milton G. Mutchnick
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  2. Glen D. Cummings
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  3. Jay H. Hoofnagle
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  4. David A. Shafritz
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Editor information

Editors and Affiliations

  1. The George Washington University School of Medicine, Washington, D.C., USA

    Allan L. Goldstein

  2. University of Rome “Tor Vergata”, Rome, Italy

    Enrico Garaci

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© 1992 Springer Science+Business Media New York

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Mutchnick, M.G., Cummings, G.D., Hoofnagle, J.H., Shafritz, D.A. (1992). Thymosin: An Innovative Approach to the Treatment of Chronic Hepatitis B. In: Goldstein, A.L., Garaci, E. (eds) Combination Therapies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3340-5_18

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  • DOI: https://doi.org/10.1007/978-1-4615-3340-5_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6472-6

  • Online ISBN: 978-1-4615-3340-5

  • eBook Packages: Springer Book Archive

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