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Developmental Regulation of Potassium Channels and the Impact on Neuronal Differentiation

  • Chapter
Ion Channels

Part of the book series: Ion Channels ((IC))

Abstract

Voltage-dependent potassium channels have a remarkable ubiquity, diversity, and importance in a wide variety of cell types. Recent progress in understanding their susceptibility to modulation by extracellular and intracellular agents and advances in the elucidation of their molecular structure have been the subject of several reviews (Rudy, 1988; jan and Jan, 1989). The present focus is prompted by emerging observations that expression of these channels in developing systems is regulated and of functional significance to subsequent differentiation of both rapid signaling capability and expression of other neuronal phenotypes.

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  1. A. B. Ribera

    Present address: Department of Physiology, University of Colorado, Health Sciences Center, Denver, Colorado, 80262, USA

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  1. Department of Biology and Center for Molecular Genetics, University of California at San Diego, La Jolla, California, 92093, USA

    A. B. Ribera & N. C. Spitzer

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  1. Northwestern University Medical School, Chicago, Illinois, USA

    Toshio Narahashi

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Ribera, A.B., Spitzer, N.C. (1992). Developmental Regulation of Potassium Channels and the Impact on Neuronal Differentiation. In: Narahashi, T. (eds) Ion Channels. Ion Channels. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3328-3_1

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