Abstract
Between the third and fifth day of development, the limb buds of avian embryos are invaded by a cell population originating from the ventrolateral edges of the adjacent dermomyotomes at wing and leg level (Christ et al. 1974, 1977, 1983; Chevallier et al. 1976; Jacob et al. 1978, 1979). These cells are known to be the precursor cells of the skeletal limb muscles. Due to their site of origin near the embryonic body axis and their destination in the limbs, the myogenic cells initially have to migrate from a medial to a more lateral position across the space between the somites and the somatopleural mesenchyme. Once they have reached the limb anlagen, the myogenic cells migrate towards the tips of the outgrowing buds (Wachtler et al. 1981, 1982; Brand et al. 1985).
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Brand-Saberi, B., Krenn, V. (1991). Observations Concerning the Control of Directed Myogenic Cell Migration. In: Hinchliffe, J.R., Hurle, J.M., Summerbell, D. (eds) Developmental Patterning of the Vertebrate Limb. NATO ASI Series, vol 205. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3310-8_37
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DOI: https://doi.org/10.1007/978-1-4615-3310-8_37
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