Abstract
The vertebrate limb bud develops as an autonomous embryonic field. The pattern of differentiation within the bud is at least in part controlled by discrete organising regions. While the interactions involved are probably complex the system can be simply modelled as three independent linear orthogonal axes. For some time the fashionable, or to use the correct molecular biology term, the sexy study, has been the antero-posterior (AP) axis and its discrete organisor, the Zone of Polarising Activity (ZPA).
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© 1991 Springer Science+Business Media New York
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Summerbell, D., Waterson, N. (1991). Does Retinoic Acid Organise a Limb or Induce a ZPA?. In: Hinchliffe, J.R., Hurle, J.M., Summerbell, D. (eds) Developmental Patterning of the Vertebrate Limb. NATO ASI Series, vol 205. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3310-8_21
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DOI: https://doi.org/10.1007/978-1-4615-3310-8_21
Publisher Name: Springer, Boston, MA
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