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All trans retinoic acid as a targeting drug for differentiation therapy in acute promyelocytic leukemia

  • Laurent Degos
Part of the Cancer Treatment and Research book series (CTAR, volume 64)

Abstract

Acute promyelocytic leukemia (APL) is a clonal expansion created by a specific translocation t(15;17) (q22;qll.21) [1] of malignant myeloid cells arrested at a specific step of maturation, leading to a characteristic morphological feature—the M3 type in the FAB (French, American, British) cytological classification [2].

Keywords

Retinoic Acid Acute Promyelocytic Leukemia Retinoic Acid Receptor Acute Promyelocytic Leukemia Patient Retinoic Acid Receptor Alpha 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 1993

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  • Laurent Degos

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